TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-952

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Salvesen GS
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Caspase-8 cleaves histone deacetylase 7 and abolishes its transcription repressor function.

Scott FL, Fuchs GJ, Boyd SE, Denault JB, Hawkins CJ, Dequiedt F, Salvesen GS

J Biol Chem. 2008 Jul 11;283(28):19499-510. doi: 10.1074/jbc.M800331200. Epub 2008 May 5. PMID: 18458084