TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: non-physiological | Merops-range: 672-711

Method

Protease identification: IN | Substrate identification: MS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

none

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Mamont P
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.

Mackay EA, Ehrhard A, Moniatte M, Guenet C, Tardif C, Tarnus C, Sorokine O, Heintzelmann B, Nay C, Remy JM, Higaki J, Van Dorsselaer A, Wagner J, Danzin C, Mamont P

Eur J Biochem. 1997 Mar 1;244(2):414-25. PMID: 9119007