TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 29-1670

Method

Substrate identification: MS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Phelps RG
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Presentation of the Goodpasture autoantigen requires proteolytic unlocking steps that destroy prominent T cell epitopes.

Zou J, Henderson L, Thomas V, Swan P, Turner AN, Phelps RG

J Am Soc Nephrol. 2007 Mar;18(3):771-9. Epub 2007 Feb 7. PMID: 17287425