TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-479

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Simon HU
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation.

Conus S, Perozzo R, Reinheckel T, Peters C, Scapozza L, Yousefi S, Simon HU

J Exp Med. 2008 Mar 17;205(3):685-98. doi: 10.1084/jem.20072152. Epub 2008 Feb 25. PMID: 18299403