TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 34-43

Method

Substrate identification: MS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Caughey GH
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

How immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolution.

Raymond WW, Trivedi NN, Makarova A, Ray M, Craik CS, Caughey GH

J Immunol. 2010 Nov 1;185(9):5360-8. doi: 10.4049/jimmunol.1002292. Epub 2010 Oct 1. PMID: 20889553