Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: physiological \| Merops-range: 29-2224
Method
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	yes
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Tracy PB - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	Proteolysis of factor V by cathepsin G and elastase indicates that cleavage at Arg1545 optimizes cofactor function by facilitating factor Xa binding. Camire RM, Kalafatis M, Tracy PB Biochemistry. 1998 Aug 25;37(34):11896-906. PMID: 9718313

Publication(s)

Proteolysis of factor V by cathepsin G and elastase indicates that cleavage at Arg1545 optimizes cofactor function by facilitating factor Xa binding.

Camire RM, Kalafatis M, Tracy PB