TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 18-303

Method

Protease identification: IN | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification.

Bossard MJ, Tomaszek TA, Thompson SK, Amegadzie BY, Hanning CR, Jones C, Kurdyla JT, McNulty DE, Drake FH, Gowen M, Levy MA

J Biol Chem. 1996 May 24;271(21):12517-24. PMID: 8647860