TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 420-433

Method

Protease identification: VT | Substrate identification: MS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells.

Obermajer N, Doljak B, Jamnik P, Fonovic UP, Kos J

Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1685-96. doi: 10.1016/j.biocel.2009.02.019. Epub 2009 Mar 6. PMID: 19433310