Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: physiological \| Merops-range: 26-132
Method	Protease identification: IN \| Substrate identification: MS
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	yes
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Taggart CC - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation. Weldon S, McNally P, McElvaney NG, Elborn JS, McAuley DF, Wartelle J, Belaaouaj A, Levine RL, Taggart CC J Immunol. 2009 Dec 15;183(12):8148-56. doi: 10.4049/jimmunol.0901716. PMID: 20007580

Publication(s)

Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation.

Weldon S, McNally P, McElvaney NG, Elborn JS, McAuley DF, Wartelle J, Belaaouaj A, Levine RL, Taggart CC