TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-1014

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Lieberman J
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.

Zhu P, Martinvalet D, Chowdhury D, Zhang D, Schlesinger A, Lieberman J

Blood. 2009 Aug 6;114(6):1205-16. doi: 10.1182/blood-2008-12-195768. Epub 2009 Jun 8. PMID: 19506301