Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-1130 |
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Method |
Protease identification: IN | Substrate identification: CS |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Craik CS - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis. Loeb CR, Harris JL, Craik CS J Biol Chem. 2006 Sep 22;281(38):28326-35. Epub 2006 Jun 23. PMID: 16798735 |
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