TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-618

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis.

Yang QH, Church-Hajduk R, Ren J, Newton ML, Du C

Genes Dev. 2003 Jun 15;17(12):1487-96. PMID: 12815069