Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 40-89 |
|---|---|
Method |
Protease identification: VT | Substrate identification: MS |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Tang WJ - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ J Mol Biol. 2010 Jan 15;395(2):430-43. doi: 10.1016/j.jmb.2009.10.072. Epub 2009 Nov 5. PMID: 19896952 |
|---|