TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 98-330

Method

Protease identification: VT | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Harding FA
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

The human G1m1 allotype associates with CD4+ T-cell responsiveness to a highly conserved IgG1 constant region peptide and confers an asparaginyl endopeptidase cleavage site.

Stickler MM, Reddy A, Xiong JM, Hinton PR, DuBridge R, Harding FA

Genes Immun. 2011 Apr;12(3):213-21. doi: 10.1038/gene.2010.68. Epub 2011 Feb 17. PMID: 21326320