Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 18-433 |
|---|---|
Method |
Substrate identification: NT |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Brandstetter H - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Activation of legumain involves proteolytic and conformational events, resulting in a context- and substrate-dependent activity profile. Dall E, Brandstetter H Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jan 1;68(Pt 1):24-31. doi: 10.1107/S1744309111048020. Epub 2011 Dec 24. PMID: 22232165 |
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