Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-269 |
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Method |
Protease identification: VT | Substrate identification: NT |
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Kaushal GP - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1beta. Herzog C, Haun RS, Kaushal V, Mayeux PR, Shah SV, Kaushal GP Biochem Biophys Res Commun. 2009 Feb 20;379(4):904-8. doi: 10.1016/j.bbrc.2008.12.161. Epub 2009 Jan 7. PMID: 19135030 |
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