TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 103-134

Method

Protease identification: VT | Substrate identification: LC

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Walther T
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Successive action of meprin A and neprilysin catabolizes B-type natriuretic peptide.

Pankow K, Wang Y, Gembardt F, Krause E, Sun X, Krause G, Schultheiss HP, Siems WE, Walther T

Circ Res. 2007 Oct 26;101(9):875-82. Epub 2007 Sep 6. PMID: 17823376