Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: physiological \| Merops-range: 1-3142
Method	Protease identification: VT \| Substrate identification: NT
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	yes
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Ellerby LM - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease. Miller JP, Holcomb J, Al-Ramahi I, de Haro M, Gafni J, Zhang N, Kim E, Sanhueza M, Torcassi C, Kwak S, Botas J, Hughes RE, Ellerby LM Neuron. 2010 Jul 29;67(2):199-212. doi: 10.1016/j.neuron.2010.06.021. PMID: 20670829

Publication(s)

Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease.

Miller JP, Holcomb J, Al-Ramahi I, de Haro M, Gafni J, Zhang N, Kim E, Sanhueza M, Torcassi C, Kwak S, Botas J, Hughes RE, Ellerby LM