TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 27-786

Method

Protease identification: VT | Substrate identification: MS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Schmelzer CE
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Degradation of tropoelastin by matrix metalloproteinases--cleavage site specificities and release of matrikines.

Heinz A, Jung MC, Duca L, Sippl W, Taddese S, Ihling C, Rusciani A, Jahreis G, Weiss AS, Neubert RH, Schmelzer CE

FEBS J. 2010 Apr;277(8):1939-56. doi: 10.1111/j.1742-4658.2010.07616.x. Epub 2010 Mar 22. PMID: 20345904