Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 30-660 |
|---|---|
Method |
|
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Murphy G - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3. Will H, Atkinson SJ, Butler GS, Smith B, Murphy G J Biol Chem. 1996 Jul 19;271(29):17119-23. PMID: 8663332 |
|---|