TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 23-197

Method

Protease identification: VT | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Miyazaki K
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Matrilysin (MMP-7) cleaves C-type lectin domain family 3 member A (CLEC3A) on tumor cell surface and modulates its cell adhesion activity.

Tsunezumi J, Higashi S, Miyazaki K

J Cell Biochem. 2009 Mar 1;106(4):693-702. doi: 10.1002/jcb.22062. PMID: 19173304