TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 2-339

Method


Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Miyazaki K
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces.

Tsunezumi J, Yamamoto K, Higashi S, Miyazaki K

FEBS J. 2008 Oct;275(19):4810-23. doi: 10.1111/j.1742-4658.2008.06620.x. Epub 2008 Aug 21. PMID: 18721140