Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 20-707 |
|---|---|
Method |
|
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Van den Steen PE - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Beta-hematin interaction with the hemopexin domain of gelatinase B/MMP-9 provokes autocatalytic processing of the propeptide, thereby priming activation by MMP-3. Geurts N, Martens E, Van Aelst I, Proost P, Opdenakker G, Van den Steen PE Biochemistry. 2008 Feb 26;47(8):2689-99. doi: 10.1021/bi702260q. Epub 2008 Feb 1. PMID: 18237197 |
|---|