TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 138-176

Method

Substrate identification: MS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Luger TA
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Terminating the stress: peripheral peptidolysis of proopiomelanocortin-derived regulatory hormones by the dermal microvascular endothelial cell extracellular peptidases neprilysin and angiotensin-converting enzyme.

Scholzen TE, Konig S, Fastrich M, Bohm M, Luger TA

Endocrinology. 2007 Jun;148(6):2793-805. Epub 2007 Mar 15. PMID: 17363457