TopFIND 4.0

Evidence Source

Description Imported from Merops: NT/MS Merops-evidence: experimental | Merops-type: physiological | Merops-range: 94-113

Method

Protease identification: IN

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

PINK1 cleavage at position A103 by the mitochondrial protease PARL.

Deas E, Plun-Favreau H, Gandhi S, Desmond H, Kjaer S, Loh SH, Renton AE, Harvey RJ, Whitworth AJ, Martins LM, Abramov AY, Wood NW

Hum Mol Genet. 2011 Mar 1;20(5):867-79. doi: 10.1093/hmg/ddq526. Epub 2010 Dec 6. PMID: 21138942