TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 20-2351

Method

Protease identification: IN | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Yoshioka A
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Mechanisms of plasmin-catalyzed inactivation of factor VIII: a crucial role for proteolytic cleavage at Arg336 responsible for plasmin-catalyzed factor VIII inactivation.

Nogami K, Shima M, Matsumoto T, Nishiya K, Tanaka I, Yoshioka A

J Biol Chem. 2007 Feb 23;282(8):5287-95. Epub 2006 Dec 21. PMID: 17189254