TopFIND 4.0

Evidence Source

Description Imported from Merops: in vivo Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-316

Method

Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Tanaka S
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand.

Hikita A, Yana I, Wakeyama H, Nakamura M, Kadono Y, Oshima Y, Nakamura K, Seiki M, Tanaka S

J Biol Chem. 2006 Dec 1;281(48):36846-55. Epub 2006 Oct 3. PMID: 17018528