TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 2-1090

Method

Protease identification: VT | Substrate identification: NT

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Huttenlocher A
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).

Chan KT, Bennin DA, Huttenlocher A

J Biol Chem. 2010 Apr 9;285(15):11418-26. doi: 10.1074/jbc.M109.090746. Epub 2010 Feb 11. PMID: 20150423