Evidence Source
| Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-844 |
|---|---|
Method |
|
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Houslay MD - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3. Consequences for altered intracellular distribution. Huston E, Beard M, McCallum F, Pyne NJ, Vandenabeele P, Scotland G, Houslay MD J Biol Chem. 2000 Sep 8;275(36):28063-74. PMID: 10829034 |
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