Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 1-233 |
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Method |
|
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Haass C - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b. Fluhrer R, Grammer G, Israel L, Condron MM, Haffner C, Friedmann E, Bohland C, Imhof A, Martoglio B, Teplow DB, Haass C Nat Cell Biol. 2006 Aug;8(8):894-6. Epub 2006 Jul 9. PMID: 16829951 |
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