TopFIND 4.0

Evidence Source

Description Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 18-477

Method

Protease identification: VT | Substrate identification: CS

Experimental system

unknown

Perturbation

none

Protease inhibitor(s) used


Directness

unknown

Physiological relevance

yes

Evidence Code(s)

    inferred from experiment

Database / Laboratory

    - Lab: Miyazaki K
    - DB: MEROPS

Raw data repository

Evidence for:

0

N-termini

0

C-termini


Publication(s)

Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis.

Jin X, Yagi M, Akiyama N, Hirosaki T, Higashi S, Lin CY, Dickson RB, Kitamura H, Miyazaki K

Cancer Sci. 2006 Dec;97(12):1327-34. Epub 2006 Sep 25. PMID: 16999819