Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: non-physiological \| Merops-range: 32-54
Method
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	none
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Bunnett NW - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia. Knecht W, Cottrell GS, Amadesi S, Mohlin J, Skaregarde A, Gedda K, Peterson A, Chapman K, Hollenberg MD, Vergnolle N, Bunnett NW J Biol Chem. 2007 Sep 7;282(36):26089-100. Epub 2007 Jul 10. PMID: 17623652

Publication(s)

Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.

Knecht W, Cottrell GS, Amadesi S, Mohlin J, Skaregarde A, Gedda K, Peterson A, Chapman K, Hollenberg MD, Vergnolle N, Bunnett NW