Evidence Source
Description | Imported from Merops: Merops-evidence: experimental | Merops-type: physiological | Merops-range: 25-108 |
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Method |
|
Experimental system |
unknown |
Perturbation |
none |
Protease inhibitor(s) used |
|
Directness |
unknown |
Physiological relevance |
yes |
Evidence Code(s) |
inferred from experiment |
Database / Laboratory |
- Lab: Steiner DF - DB: MEROPS |
Raw data repository |
Evidence for:
0
N-termini
0
C-termini
Publication(s) |
Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2. Furuta M, Carroll R, Martin S, Swift HH, Ravazzola M, Orci L, Steiner DF J Biol Chem. 1998 Feb 6;273(6):3431-7. PMID: 9452465 |
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