Evidence Source

Description	Imported from Merops: Merops-evidence: experimental \| Merops-type: physiological \| Merops-range: 19-2531
Method
Experimental system	unknown
Perturbation	none
Protease inhibitor(s) used
Directness	unknown
Physiological relevance	yes
Evidence Code(s)	inferred from experiment
Database / Laboratory	- Lab: Haass C - DB: MEROPS
Raw data repository

Evidence for:

Publication(s)	Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. Okochi M, Steiner H, Fukumori A, Tanii H, Tomita T, Tanaka T, Iwatsubo T, Kudo T, Takeda M, Haass C EMBO J. 2002 Oct 15;21(20):5408-16. PMID: 12374741

Publication(s)

Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

Okochi M, Steiner H, Fukumori A, Tanii H, Tomita T, Tanaka T, Iwatsubo T, Kudo T, Takeda M, Haass C

EMBO J. 2002 Oct 15;21(20):5408-16. PMID: 12374741