TopFIND 4.0

A0PK05: Transmembrane protein 72

General Information

Protein names
- Transmembrane protein 72
- Kidney-specific secretory protein of 37 kDa
Gene names TMEM72
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID A0PK05

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQLQVFWTGL EYTCRLLGIT TAAVLIGVGT ETFLQGQFKS LAFYLLFTGA AVSICEGAYF 
        70         80         90        100        110        120 
VAQLLAICFQ CQPGSLADRV REKAHWLGCF QKFLAYLLLS VACFLHPVLV WHVTIPGSML 
       130        140        150        160        170        180 
IITGLAYFLL SKRKKRKAAP EVLASPEQYT DPSSSAVSTT GSGDTEQTYT FHGALKEGPS 
       190        200        210        220        230        240 
SLFIHMKSIL KGTKKPSALQ PPNTLMELSL EPADSLAKKK QVHFEDNLVR IVPSLAEGLD 
       250        260        270    
DGDSEPEETT SDTTPIIPPP QAPLFLSSLT ATGLF

Isoforms

- Isoform 2 of Transmembrane protein 72

Sequence View

        10         20         30         40         50         60 
MQLQVFWTGL EYTCRLLGIT TAAVLIGVGT ETFLQGQFKS LAFYLLFTGA AVSICEGAYF 
        70         80         90        100        110        120 
VAQLLAICFQ CQPGSLADRV REKAHWLGCF QKFLAYLLLS VACFLHPVLV WHVTIPGSML 
       130        140        150        160        170        180 
IITGLAYFLL SKRKKRKAAP EVLASPEQYT DPSSSAVSTT GSGDTEQTYT FHGALKEGPS 
       190        200        210        220        230        240 
SLFIHMKSIL KGTKKPSALQ PPNTLMELSL EPADSLAKKK QVHFEDNLVR IVPSLAEGLD 
       250        260        270    
DGDSEPEETT SDTTPIIPPP QAPLFLSSLT ATGLF



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    A0PK05-1-unknown MQLQVF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    A0PK05-119-unknown MLIITG... 119 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92518

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ATGLF 275 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ATGLF 275 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88136

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)