A2AR50: Ras-specific guanine nucleotide-releasing factor RalGPS1

General Information

Protein names	- Ras-specific guanine nucleotide-releasing factor RalGPS1 - Ral GEF with PH domain and SH3-binding motif 1 - Ral guanine nucleotide exchange factor 2 - RalGEF 2 - RalA exchange factor RalGPS1
Gene names	Ralgps1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	A2AR50

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTRDY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSS SARFRRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNLMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLTHTSST AITNGLSLGS SESSEFSEEM SAGLESRGRL
       430        440        450        460        470        480
YATLGPNWRV PVRNSPRTRS CVYSPTSPCT CTVGSSATVP TMEGPLRRKT LLKEGRKPAL
       490        500        510        520        530        540
SSWTRYWVVL SGATLLYYGA KSLRGTDRKH YKSTPGKKVS IVGWMVQLPD DPEHPDIFQL
       550        560        570        580
NNPDKGNVYK FQTGSRFHAI LWHKHLDDAC KSSRPQVPAN LMSFE

Isoforms

- Isoform 2 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 3 of Ras-specific guanine nucleotide-releasing factor RalGPS1 - Isoform 4 of Ras-specific guanine nucleotide-releasing factor RalGPS1

Sequence View

        10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTRDY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSS SARFRRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNLMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLTHTSST AITNGLSLGS SESSEFSEEM SAGLESRGRL
       430        440        450        460        470        480
YATLGPNWRV PVRNSPRTRS CVYSPTSPCT CTVGSSATVP TMEGPLRRKT LLKEGRKPAL
       490        500        510        520        530        540
SSWTRYWVVL SGATLLYYGA KSLRGTDRKH YKSTPGKKVS IVGWMVQLPD DPEHPDIFQL
       550        560        570        580
NNPDKGNVYK FQTGSRFHAI LWHKHLDDAC KSSRPQVPAN LMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTRDY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSS SARFRRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNLMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLTHTSST AITNGLSLGS SESSEFSEEM SAGLESRGRL
       430        440        450        460        470        480
YATLGPNWRV PVRNSPRTRS CVYSPTSPCT CTVGSSATVP TMEGPLRRKT LLKEGRKPAL
       490        500        510        520        530        540
SSWTRYWVVL SGATLLYYGA KSLRGTDRKH YKSTPGKKVS IVGWMVQLPD DPEHPDIFQL
       550        560        570        580
NNPDKGNVYK FQTGSRFHAI LWHKHLDDAC KSSRPQVPAN LMSFE         10         20         30         40         50         60
MYKRNGLMAS VLVTSATPQG SSSSDSLEGQ SCDYASKSYD AVVFDVLKVT PEEFASQITL
        70         80         90        100        110        120
MDIPVFKAIQ PEELASCGWS KKEKHSLAPN VVAFTRRFNQ VSFWVVREIL TAQTLKIRAE
       130        140        150        160        170        180
ILSHFVKIAK KLLELNNLHS LMSVVSALQS APIFRLTKTW ALLNRKDKTT FEKLDYLMSK
       190        200        210        220        230        240
EDNYKRTRDY IRSLKMVPSI PYLGIYLLDL IYIDSAYPAS GSIMENEQRS NQMNNILRII
       250        260        270        280        290        300
ADLQVSCSYD HLTTLPHVQK YLKSVRYIEE LQKFVEDDNY KLSLRIEPGS SSPRLVSSKE
       310        320        330        340        350        360
DLAGPSAGSS SARFRRRPTC PDTSVAGSLP TPPVPRHRKS HSLGNNLMCQ LSVVESKSAT
       370        380        390        400        410        420
FPSEKARHLL DDSVLESRSP RRGLTHTSST AITNGLSLGS SESSEFSEEM SAGLESRGRL
       430        440        450        460        470        480
YATLGPNWRV PVRNSPRTRS CVYSPTSPCT CTVGSSATVP TMEGPLRRKT LLKEGRKPAL
       490        500        510        520        530        540
SSWTRYWVVL SGATLLYYGA KSLRGTDRKH YKSTPGKKVS IVGWMVQLPD DPEHPDIFQL
       550        560        570        580
NNPDKGNVYK FQTGSRFHAI LWHKHLDDAC KSSRPQVPAN LMSFE

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
A2AR50-1-unknown	MYKRNG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
A2AR50-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87453
A2AR50-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87454
A2AR50-1-unknown	MYKRNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87455

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LMSFE	585	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LMSFE	585	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83071
...LMSFE	585	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83072

TopFIND

A2AR50: Ras-specific guanine nucleotide-releasing factor RalGPS1

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

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Methodology:

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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates