A2VEC9: SCO-spondin {ECO:0000305}
| Protein names | - SCO-spondin {ECO:0000305} |
|---|---|
| Gene names | SSPO |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | A2VEC9 |
3
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLLPALLFGM AWALADGRWC EWTETIRVEE EVAPRQEDLV PCASLDHYSR LGWRLDLPWS
70 80 90 100 110 120
GRSGLTRSPA PGLCPIYKPP ETRPAKWNRT VRTCCPGWGG AHCTEALAKA SPEGHCFAMW
130 140 150 160 170 180
QCQLQAGSAN ASAGSLEECC ARPWGQSWWD GSSQACRSCS SRHLPGSASS PALLQPLAGA
190 200 210 220 230 240
VGQLWSQHQR PSATCASWSG FHYRTFDGRH YHFLGRCTYL LAGAADSTWA VHLTPGDRCP
250 260 270 280 290 300
QPGHCQRVTM GPEEVLIQAG NVSVKGQLVP EGQSWLLHGL SLQWLGDWLV LSGGLGVVVR
310 320 330 340 350 360
LDRTGSISIS VDHELWGQTQ GLCGLYNGWP EDDFMEPGGG LAMLAATFGN SWRLPGSESG
370 380 390 400 410 420
CLDAVEVAQG CDSPLGLIDA DVEPGHLRAE AQDVCHQLLE GPFGQCHAQV SPAEYHEACL
430 440 450 460 470 480
FAYCAGAMAG SGQEGRQQAV CATFASYVQA CARRHIHIRW RKPGFCERLC PGGQLYSDCV
490 500 510 520 530 540
SLCPPSCEAV GQGEEESCRE ECVSGCECPR GLFWNGTLCV PAAHCPCYYC RQRYVPGDTV
550 560 570 580 590 600
RQLCNPCVCR DGRWHCAQAL CPAECAVGGD GHYLTFDGRS YSFWGGQGCR YSLVQDYVKG
610 620 630 640 650 660
QLLILLEHGA CDAGSCLHAI SVSLEDTHIQ LRDSGAVLVN GQDVGLPWIG AEGLSVRRAS
670 680 690 700 710 720
SAFLLLRWPG AQVLWGLSDP VAYITLDPRH AHQVQGLCGT FTQNQQDDFL TPAGDVETSI
730 740 750 760 770 780
AAFASKFQVA GKGRCPSEDS ALLSPCTTHS QRHAFAEAAC AILHSSVFQE CHRLVDKEPF
790 800 810 820 830 840
YLRCLAAVCG CDPGSDCLCP VLSAYARRCA QEGASPPWRN QTLCPVMCPG GQEYRECAPA
850 860 870 880 890 900
CGQHCGKPED CGELGSCVAG CNCPLGLLWD PEGQCVPPSL CPCQLGARRY APGSATMKEC
910 920 930 940 950 960
NRCICQERGL WNCTARHCPS QAFCPRELVY APGACLLTCD SPSANHSCPA GSTDGCVCPP
970 980 990 1000 1010 1020
GTVLLDERCV PPDLCPCRHS GQWYLPNATI QEDCNVCVCR GRQWHCTGQR RSGRCQASGA
1030 1040 1050 1060 1070 1080
PHYVTFDGLA FTYPGACEYL LVREASGLFT VSAQNLPCGA SGLTCTKALA VRLEGTVVHM
1090 1100 1110 1120 1130 1140
LRGRAVTVNG VSVTPPKVYT GPGLSLRRAG LFLLLSTHLG LTLLWDGGTR VLVQLSPQFR
1150 1160 1170 1180 1190 1200
GRVAGLCGDF DGDASNDLRS RQGVLEPTAE LAAHSWRLSP LCPEPGDLPH PCTMNTHRAG
1210 1220 1230 1240 1250 1260
WARARCGALL QPLFTLCHAE VPPQQHYEWC LYDACGCDSG GDCECLCSAI ATYADECARH
1270 1280 1290 1300 1310 1320
GHHVRWRSQE LCSLQCEGGQ VYEACGPTCP PTCHEQHPEP GWHCQVVACV EGCFCPEGTL
1330 1340 1350 1360 1370 1380
LHGGACLEPA SCPCEWGRNS FPPGSVLQKD CGNCTCQEGQ WHCGGDGGHC EELVPACAEG
1390 1400 1410 1420 1430 1440
EALCQENGHC VPHGWLCDNQ DDCGDGSDEE GCAAPGCGEG QMTCSSGHCL PLALLCDRQD
1450 1460 1470 1480 1490 1500
DCGDGTDEPS YPCPQGLLAC ADGRCLPPAL LCDGHPDCLD AADEESCLGQ VTCVPGEVSC
1510 1520 1530 1540 1550 1560
VDGTCLGAIQ LCDGVWDCPD GADEGPGHCP LPSLPTPPAS TLPGPSPGSL DTASSPLASA
1570 1580 1590 1600 1610 1620
SPAPPCGPFE FRCGSGECTP RGWRCDQEED CADGSDERGC GGPCAPHHAP CARGPHCVSP
1630 1640 1650 1660 1670 1680
EQLCDGVRQC PDGSDEGPDA CGGLPALGGP NRTGLPCPEY TCPNGTCIGF QLVCDGQPDC
1690 1700 1710 1720 1730 1740
GRPGQVGPSP EEQGCGAWGP WSPWGPCSRT CGPWGQGRSR RCSPLGLLVL QNCPGPEHQS
1750 1760 1770 1780 1790 1800
QACFTAACPV DGEWSTWSPW SVCSEPCRGT MTRQRQCHSP QNGGRTCAAL PGGLHSTRQT
1810 1820 1830 1840 1850 1860
KPCPQDGCPN ATCSGELMFQ PCAPCPLTCD DISGQVTCPP DWPCGSPGCW CPEGQVLGSE
1870 1880 1890 1900 1910 1920
GWCVWPRQCP CLVDGARYWP GQRIKADCQL CICQDGRPRR CRLNPDCAVD CGWSSWSPWA
1930 1940 1950 1960 1970 1980
KCLGPCGSQS IQWSFRSSNN PRPSGRGRQC RGIHRKARRC QTEPCEGCEH QGQVHRVGER
1990 2000 2010 2020 2030 2040
WHGGPCRVCQ CLHNLTAHCS PYCPLGSCPQ GWVLVEGTGE SCCHCALPGE NQTVQPMATP
2050 2060 2070 2080 2090 2100
AAAPAPSPQI RFPLATYILP PSGDPCYSPL GLAGLAEGSL HASSQQLEHP TQAALLGAPT
2110 2120 2130 2140 2150 2160
QGPSPQGWHA GGDAYAKWHT RPHYLQLDLL QPRNLTGILV PETGSSNAYA SSFSLQFSSN
2170 2180 2190 2200 2210 2220
GLHWHDYRDL LPGILPLPKL FPRNWDDLDP AVWTFGRMVQ ARFVRVWPHD VHHSDVPLQV
2230 2240 2250 2260 2270 2280
ELLGCEPGSP PAPLCPGVGL RCASGECVLR GGPCDGVLDC EDGSDEEGCV LLPEGTGRFH
2290 2300 2310 2320 2330 2340
STAKTLALSS AQPGQLLHWP REGLAETEHW PPGQESPTSP TETRPVSPGP ASGVPHHGES
2350 2360 2370 2380 2390 2400
VQMVTTTPIP QMEARTLPPG MAAVTVVPPH PVTPATPAGQ SVAPGPFPPV QCGPGQTPCE
2410 2420 2430 2440 2450 2460
VLGCVEQAQV CDGREDCLDG SDERHCARNL LMWLPSLPAL WAASTVPFMM PTMALPGLPA
2470 2480 2490 2500 2510 2520
SRALCSPSQL SCGSGECLSA ERRCDLRPDC QDGSDEDGCV DCVLAPWSVW SSCSRSCGLG
2530 2540 2550 2560 2570 2580
LTFQRQELLR PPLPGGSCPR DRFRSQSCFV QACPVAGAWA MWEAWGPCSV SCGGGHQSRQ
2590 2600 2610 2620 2630 2640
RSCVDPPPKN GGAPCPGASQ ERAPCGLQPC SGGTDCELGR VYVSADLCQK GLVPPCPPSC
2650 2660 2670 2680 2690 2700
LDPKANRSCS GHCVEGCRCP PGLLLHDTRC LPLSECPCLV GEELKWPGVS FLLGNCSQCV
2710 2720 2730 2740 2750 2760
CEKGELLCQP GGCPLPCGWS AWSSWAPCDR SCGSGVRARF RSPSNPPAAW GGAPCEGDRQ
2770 2780 2790 2800 2810 2820
ELQGCHTVCG TEVFGWTPWT SWSSCSQSCL APGGGPGWRS RSRLCPSPGD SSCPGDATQE
2830 2840 2850 2860 2870 2880
EPCSPPVCPV PSIWGLWAPW STCSAPCDGG IQTRGRSCSS LAPGDTTCPG PHSQTRDCNT
2890 2900 2910 2920 2930 2940
QPCTAQCPEN MLFRSAEQCH QEGGPCPRLC LTQGPGIECT GFCAPGCTCP PGLFLHNASC
2950 2960 2970 2980 2990 3000
LPRSQCPCQL HGQLYASGAM ARLDSCNNCT CVSGKMACTS ERCPVACGWS PWTLWSLCSC
3010 3020 3030 3040 3050 3060
SCNVGIRRRF RAGTAPPAAF GGAECQGPTM EAEFCSLRPC PGPGGEWGPW SPCSVPCGGG
3070 3080 3090 3100 3110 3120
YRNRTRGSSR SLMEFSTCGL QPCAGPVPGM CPRDKQWLDC AQGPASCAEL SAPRGTNQTC
3130 3140 3150 3160 3170 3180
HPGCHCPSGM LLLNNVCVPT QDCPCAHEGH LYPPGSTVVR PCENCSCVSG LIANCSSWPC
3190 3200 3210 3220 3230 3240
AEGEPTWSPW TPWSQCSASC GPARCHRHRF CARSPSAVPS TVAPLPLPAT PTPLCSGPEA
3250 3260 3270 3280 3290 3300
EEEPCLLQGC DRAGGWGPWG PWSHCSRSCG GGLRSRTRAC DQPPPQGLGD YCEGPRAQGE
3310 3320 3330 3340 3350 3360
VCQALPCPVT NCTAIEGAEY SPCGPPCPRS CDDLVHCVWR CQPGCYCPPG QVLSSNGAIC
3370 3380 3390 3400 3410 3420
VQPGHCSCLD LLTGQRHHPG ARLARPDGCN HCTCLEGRLN CTDLPCPVPG GWCPWSEWTM
3430 3440 3450 3460 3470 3480
CSQPCRGQTR SRSRACACPT PQHGGAPCTG EAGEAGAQHQ REACPSYATC PVDGAWGPWG
3490 3500 3510 3520 3530 3540
PWSPCDMCLG QSHRSRACSR PPTPEGGRPC PGNHTQSRPC QENSTQCTDC GGGQSLHPCG
3550 3560 3570 3580 3590 3600
QPCPRSCQDL SPGSVCQPGS VGCQPTCGCP LGQLSQDGLC VPPAHCRCQY QPGAMGIPEN
3610 3620 3630 3640 3650 3660
QSRSAGSRFS SWESLEPGEV VTGPCDNCTC VAGILQCQEV PDCPDPGVWS SWGPWEDCSV
3670 3680 3690 3700 3710 3720
SCGGGEQLRS RRCARPPCPG PARQSRTCST QVCREAGCPA GRLYRECQPG EGCPFSCAHV
3730 3740 3750 3760 3770 3780
TQQVGCFSEG CEEGCHCPEG TFQHRLACVQ ECPCVLTAWL LQELGATIGD PGQPLGPGDE
3790 3800 3810 3820 3830 3840
LDSGQTLRTS CGNCSCAHGK LSCSLDDCFE ADGGFGPWSP WGPCSRSCGG LGTRTRSRQC
3850 3860 3870 3880 3890 3900
VLTMPTLSGQ GCRGPRQDLE YCPSPDCPGA EGSTVEPVTG LPGGWGPWSS WSPCSRSCTD
3910 3920 3930 3940 3950 3960
PARPAWRSRT RLCLANCTMG DPLQERPCNL PSCTELPVCP GPGCGAGNCS WTSWAPWEPC
3970 3980 3990 4000 4010 4020
SRSCGVGQQR RLRAYRPPGP GGHWCPNILT AYQERRFCNL RACPVPGGWS RWSPWSWCDR
4030 4040 4050 4060 4070 4080
SCGGGQSLRS RSCSSPPSKN GGAPCAGERH QARLCNPMPC EAGCPAGMEV VTCANRCPRR
4090 4100 4110 4120 4130 4140
CSDLQEGIVC QDDQVCQKGC RCPKGSLEQD GGCVPIGHCD CTDAQGHSWA PGSQHQDACN
4150 4160 4170 4180 4190 4200
NCSCQAGQLS CTAQPCPPPT HCAWSHWSAW SPCSHSCGPR GQQSRFRSST SGSWAPECRE
4210 4220 4230 4240 4250 4260
EQSQSQPCPQ PSCPPLCLQG TRSRTLGDSW LQGECQRCSC TPEGVICEDT ECAVPEAWTL
4270 4280 4290 4300 4310 4320
WSSWSDCPVS CGGGNQVRTR ACRAAAPHHR SPPCLGPDTQ TRQQPCPGLL EACSWGPWGP
4330 4340 4350 4360 4370 4380
CSRSCGPGLA SRSGSCPCLM AKADPTCNST FLHLDTQGCY SGPCPEECVW SSWSSWTRCS
4390 4400 4410 4420 4430 4440
CRVLVQQRYR HQGPASRGAR AGAPCTRLDG HFRPCLISNC SEDSCTPPFE FHACGSPCAG
4450 4460 4470 4480 4490 4500
LCATHLSHQL CQDLPPCQPG CYCPKGLLEQ AGGCIPPEEC NCWHTSAAGA GMTLAPGDRL
4510 4520 4530 4540 4550 4560
QLGCKECECR RGELHCTSQG CQGLLPLSEW SEWSPCGPCL PPSALAPASR TALEEHWLRD
4570 4580 4590 4600 4610 4620
PTGLSPTLAP LLASEQHRHR LCLDPATGRP WTGAPHLCTA PLSQQRLCPD PGACPDSCQW
4630 4640 4650 4660 4670 4680
SLWGPWSPCQ VPCSGGFRLR WREAEALCGG GCREPWAQES CNGGPCPESC EAQDTVFTLD
4690 4700 4710 4720 4730 4740
CANQCPHSCA DLWDRVQCLQ GPCRPGCRCP PGQLVQDGRC VPISSCRCGL PSANASWELA
4750 4760 4770 4780 4790 4800
PAQAVQLDCQ NCTCVNESLV CPHQECPVLG PWSAWSSCSA PCGGGTMERH RTCEGGPGVA
4810 4820 4830 4840 4850 4860
PCQAQDTEQR QECNLQPCPE CPPGQVLSAC ATSCPCLCWH LQPGAICVQE PCQPGCGCPG
4870 4880 4890 4900 4910 4920
GQLLHNGTCV PPTACPCTQH SLPWGLTLTL EEQAQELPPG TVLTRNCTRC VCHGGAFSCS
4930 4940 4950 4960 4970 4980
LVDCQVPPGE TWQQVAPGEL GLCEQTCLEM NATKTQSNCS SARASGCVCQ PGHFRSQAGP
4990 5000 5010 5020 5030 5040
CVPEDHCECW HLGRPHLPGS EWQEACESCL CLSGRPVCTQ HCSPLTCAQG EEMVLEPGSC
5050 5060 5070 5080 5090 5100
CPSCRREAPE EQSPSCQLLT ELRNFTKGTC YLDQVEVSYC SGYCPSSTHV MPEEPYLQSQ
5110 5120 5130 5140 5150
CDCCSYRLDP ESPVRILNLR CLGGHTEPVV LPVIHSCQCS SCQGGDFSKR
Isoforms
- Isoform 2 of SCO-spondin - Isoform 2 of SCO-spondinSequence View
10 20 30 40 50 60
MLLPALLFGM AWALADGRWC EWTETIRVEE EVAPRQEDLV PCASLDHYSR LGWRLDLPWS
70 80 90 100 110 120
GRSGLTRSPA PGLCPIYKPP ETRPAKWNRT VRTCCPGWGG AHCTEALAKA SPEGHCFAMW
130 140 150 160 170 180
QCQLQAGSAN ASAGSLEECC ARPWGQSWWD GSSQACRSCS SRHLPGSASS PALLQPLAGA
190 200 210 220 230 240
VGQLWSQHQR PSATCASWSG FHYRTFDGRH YHFLGRCTYL LAGAADSTWA VHLTPGDRCP
250 260 270 280 290 300
QPGHCQRVTM GPEEVLIQAG NVSVKGQLVP EGQSWLLHGL SLQWLGDWLV LSGGLGVVVR
310 320 330 340 350 360
LDRTGSISIS VDHELWGQTQ GLCGLYNGWP EDDFMEPGGG LAMLAATFGN SWRLPGSESG
370 380 390 400 410 420
CLDAVEVAQG CDSPLGLIDA DVEPGHLRAE AQDVCHQLLE GPFGQCHAQV SPAEYHEACL
430 440 450 460 470 480
FAYCAGAMAG SGQEGRQQAV CATFASYVQA CARRHIHIRW RKPGFCERLC PGGQLYSDCV
490 500 510 520 530 540
SLCPPSCEAV GQGEEESCRE ECVSGCECPR GLFWNGTLCV PAAHCPCYYC RQRYVPGDTV
550 560 570 580 590 600
RQLCNPCVCR DGRWHCAQAL CPAECAVGGD GHYLTFDGRS YSFWGGQGCR YSLVQDYVKG
610 620 630 640 650 660
QLLILLEHGA CDAGSCLHAI SVSLEDTHIQ LRDSGAVLVN GQDVGLPWIG AEGLSVRRAS
670 680 690 700 710 720
SAFLLLRWPG AQVLWGLSDP VAYITLDPRH AHQVQGLCGT FTQNQQDDFL TPAGDVETSI
730 740 750 760 770 780
AAFASKFQVA GKGRCPSEDS ALLSPCTTHS QRHAFAEAAC AILHSSVFQE CHRLVDKEPF
790 800 810 820 830 840
YLRCLAAVCG CDPGSDCLCP VLSAYARRCA QEGASPPWRN QTLCPVMCPG GQEYRECAPA
850 860 870 880 890 900
CGQHCGKPED CGELGSCVAG CNCPLGLLWD PEGQCVPPSL CPCQLGARRY APGSATMKEC
910 920 930 940 950 960
NRCICQERGL WNCTARHCPS QAFCPRELVY APGACLLTCD SPSANHSCPA GSTDGCVCPP
970 980 990 1000 1010 1020
GTVLLDERCV PPDLCPCRHS GQWYLPNATI QEDCNVCVCR GRQWHCTGQR RSGRCQASGA
1030 1040 1050 1060 1070 1080
PHYVTFDGLA FTYPGACEYL LVREASGLFT VSAQNLPCGA SGLTCTKALA VRLEGTVVHM
1090 1100 1110 1120 1130 1140
LRGRAVTVNG VSVTPPKVYT GPGLSLRRAG LFLLLSTHLG LTLLWDGGTR VLVQLSPQFR
1150 1160 1170 1180 1190 1200
GRVAGLCGDF DGDASNDLRS RQGVLEPTAE LAAHSWRLSP LCPEPGDLPH PCTMNTHRAG
1210 1220 1230 1240 1250 1260
WARARCGALL QPLFTLCHAE VPPQQHYEWC LYDACGCDSG GDCECLCSAI ATYADECARH
1270 1280 1290 1300 1310 1320
GHHVRWRSQE LCSLQCEGGQ VYEACGPTCP PTCHEQHPEP GWHCQVVACV EGCFCPEGTL
1330 1340 1350 1360 1370 1380
LHGGACLEPA SCPCEWGRNS FPPGSVLQKD CGNCTCQEGQ WHCGGDGGHC EELVPACAEG
1390 1400 1410 1420 1430 1440
EALCQENGHC VPHGWLCDNQ DDCGDGSDEE GCAAPGCGEG QMTCSSGHCL PLALLCDRQD
1450 1460 1470 1480 1490 1500
DCGDGTDEPS YPCPQGLLAC ADGRCLPPAL LCDGHPDCLD AADEESCLGQ VTCVPGEVSC
1510 1520 1530 1540 1550 1560
VDGTCLGAIQ LCDGVWDCPD GADEGPGHCP LPSLPTPPAS TLPGPSPGSL DTASSPLASA
1570 1580 1590 1600 1610 1620
SPAPPCGPFE FRCGSGECTP RGWRCDQEED CADGSDERGC GGPCAPHHAP CARGPHCVSP
1630 1640 1650 1660 1670 1680
EQLCDGVRQC PDGSDEGPDA CGGLPALGGP NRTGLPCPEY TCPNGTCIGF QLVCDGQPDC
1690 1700 1710 1720 1730 1740
GRPGQVGPSP EEQGCGAWGP WSPWGPCSRT CGPWGQGRSR RCSPLGLLVL QNCPGPEHQS
1750 1760 1770 1780 1790 1800
QACFTAACPV DGEWSTWSPW SVCSEPCRGT MTRQRQCHSP QNGGRTCAAL PGGLHSTRQT
1810 1820 1830 1840 1850 1860
KPCPQDGCPN ATCSGELMFQ PCAPCPLTCD DISGQVTCPP DWPCGSPGCW CPEGQVLGSE
1870 1880 1890 1900 1910 1920
GWCVWPRQCP CLVDGARYWP GQRIKADCQL CICQDGRPRR CRLNPDCAVD CGWSSWSPWA
1930 1940 1950 1960 1970 1980
KCLGPCGSQS IQWSFRSSNN PRPSGRGRQC RGIHRKARRC QTEPCEGCEH QGQVHRVGER
1990 2000 2010 2020 2030 2040
WHGGPCRVCQ CLHNLTAHCS PYCPLGSCPQ GWVLVEGTGE SCCHCALPGE NQTVQPMATP
2050 2060 2070 2080 2090 2100
AAAPAPSPQI RFPLATYILP PSGDPCYSPL GLAGLAEGSL HASSQQLEHP TQAALLGAPT
2110 2120 2130 2140 2150 2160
QGPSPQGWHA GGDAYAKWHT RPHYLQLDLL QPRNLTGILV PETGSSNAYA SSFSLQFSSN
2170 2180 2190 2200 2210 2220
GLHWHDYRDL LPGILPLPKL FPRNWDDLDP AVWTFGRMVQ ARFVRVWPHD VHHSDVPLQV
2230 2240 2250 2260 2270 2280
ELLGCEPGSP PAPLCPGVGL RCASGECVLR GGPCDGVLDC EDGSDEEGCV LLPEGTGRFH
2290 2300 2310 2320 2330 2340
STAKTLALSS AQPGQLLHWP REGLAETEHW PPGQESPTSP TETRPVSPGP ASGVPHHGES
2350 2360 2370 2380 2390 2400
VQMVTTTPIP QMEARTLPPG MAAVTVVPPH PVTPATPAGQ SVAPGPFPPV QCGPGQTPCE
2410 2420 2430 2440 2450 2460
VLGCVEQAQV CDGREDCLDG SDERHCARNL LMWLPSLPAL WAASTVPFMM PTMALPGLPA
2470 2480 2490 2500 2510 2520
SRALCSPSQL SCGSGECLSA ERRCDLRPDC QDGSDEDGCV DCVLAPWSVW SSCSRSCGLG
2530 2540 2550 2560 2570 2580
LTFQRQELLR PPLPGGSCPR DRFRSQSCFV QACPVAGAWA MWEAWGPCSV SCGGGHQSRQ
2590 2600 2610 2620 2630 2640
RSCVDPPPKN GGAPCPGASQ ERAPCGLQPC SGGTDCELGR VYVSADLCQK GLVPPCPPSC
2650 2660 2670 2680 2690 2700
LDPKANRSCS GHCVEGCRCP PGLLLHDTRC LPLSECPCLV GEELKWPGVS FLLGNCSQCV
2710 2720 2730 2740 2750 2760
CEKGELLCQP GGCPLPCGWS AWSSWAPCDR SCGSGVRARF RSPSNPPAAW GGAPCEGDRQ
2770 2780 2790 2800 2810 2820
ELQGCHTVCG TEVFGWTPWT SWSSCSQSCL APGGGPGWRS RSRLCPSPGD SSCPGDATQE
2830 2840 2850 2860 2870 2880
EPCSPPVCPV PSIWGLWAPW STCSAPCDGG IQTRGRSCSS LAPGDTTCPG PHSQTRDCNT
2890 2900 2910 2920 2930 2940
QPCTAQCPEN MLFRSAEQCH QEGGPCPRLC LTQGPGIECT GFCAPGCTCP PGLFLHNASC
2950 2960 2970 2980 2990 3000
LPRSQCPCQL HGQLYASGAM ARLDSCNNCT CVSGKMACTS ERCPVACGWS PWTLWSLCSC
3010 3020 3030 3040 3050 3060
SCNVGIRRRF RAGTAPPAAF GGAECQGPTM EAEFCSLRPC PGPGGEWGPW SPCSVPCGGG
3070 3080 3090 3100 3110 3120
YRNRTRGSSR SLMEFSTCGL QPCAGPVPGM CPRDKQWLDC AQGPASCAEL SAPRGTNQTC
3130 3140 3150 3160 3170 3180
HPGCHCPSGM LLLNNVCVPT QDCPCAHEGH LYPPGSTVVR PCENCSCVSG LIANCSSWPC
3190 3200 3210 3220 3230 3240
AEGEPTWSPW TPWSQCSASC GPARCHRHRF CARSPSAVPS TVAPLPLPAT PTPLCSGPEA
3250 3260 3270 3280 3290 3300
EEEPCLLQGC DRAGGWGPWG PWSHCSRSCG GGLRSRTRAC DQPPPQGLGD YCEGPRAQGE
3310 3320 3330 3340 3350 3360
VCQALPCPVT NCTAIEGAEY SPCGPPCPRS CDDLVHCVWR CQPGCYCPPG QVLSSNGAIC
3370 3380 3390 3400 3410 3420
VQPGHCSCLD LLTGQRHHPG ARLARPDGCN HCTCLEGRLN CTDLPCPVPG GWCPWSEWTM
3430 3440 3450 3460 3470 3480
CSQPCRGQTR SRSRACACPT PQHGGAPCTG EAGEAGAQHQ REACPSYATC PVDGAWGPWG
3490 3500 3510 3520 3530 3540
PWSPCDMCLG QSHRSRACSR PPTPEGGRPC PGNHTQSRPC QENSTQCTDC GGGQSLHPCG
3550 3560 3570 3580 3590 3600
QPCPRSCQDL SPGSVCQPGS VGCQPTCGCP LGQLSQDGLC VPPAHCRCQY QPGAMGIPEN
3610 3620 3630 3640 3650 3660
QSRSAGSRFS SWESLEPGEV VTGPCDNCTC VAGILQCQEV PDCPDPGVWS SWGPWEDCSV
3670 3680 3690 3700 3710 3720
SCGGGEQLRS RRCARPPCPG PARQSRTCST QVCREAGCPA GRLYRECQPG EGCPFSCAHV
3730 3740 3750 3760 3770 3780
TQQVGCFSEG CEEGCHCPEG TFQHRLACVQ ECPCVLTAWL LQELGATIGD PGQPLGPGDE
3790 3800 3810 3820 3830 3840
LDSGQTLRTS CGNCSCAHGK LSCSLDDCFE ADGGFGPWSP WGPCSRSCGG LGTRTRSRQC
3850 3860 3870 3880 3890 3900
VLTMPTLSGQ GCRGPRQDLE YCPSPDCPGA EGSTVEPVTG LPGGWGPWSS WSPCSRSCTD
3910 3920 3930 3940 3950 3960
PARPAWRSRT RLCLANCTMG DPLQERPCNL PSCTELPVCP GPGCGAGNCS WTSWAPWEPC
3970 3980 3990 4000 4010 4020
SRSCGVGQQR RLRAYRPPGP GGHWCPNILT AYQERRFCNL RACPVPGGWS RWSPWSWCDR
4030 4040 4050 4060 4070 4080
SCGGGQSLRS RSCSSPPSKN GGAPCAGERH QARLCNPMPC EAGCPAGMEV VTCANRCPRR
4090 4100 4110 4120 4130 4140
CSDLQEGIVC QDDQVCQKGC RCPKGSLEQD GGCVPIGHCD CTDAQGHSWA PGSQHQDACN
4150 4160 4170 4180 4190 4200
NCSCQAGQLS CTAQPCPPPT HCAWSHWSAW SPCSHSCGPR GQQSRFRSST SGSWAPECRE
4210 4220 4230 4240 4250 4260
EQSQSQPCPQ PSCPPLCLQG TRSRTLGDSW LQGECQRCSC TPEGVICEDT ECAVPEAWTL
4270 4280 4290 4300 4310 4320
WSSWSDCPVS CGGGNQVRTR ACRAAAPHHR SPPCLGPDTQ TRQQPCPGLL EACSWGPWGP
4330 4340 4350 4360 4370 4380
CSRSCGPGLA SRSGSCPCLM AKADPTCNST FLHLDTQGCY SGPCPEECVW SSWSSWTRCS
4390 4400 4410 4420 4430 4440
CRVLVQQRYR HQGPASRGAR AGAPCTRLDG HFRPCLISNC SEDSCTPPFE FHACGSPCAG
4450 4460 4470 4480 4490 4500
LCATHLSHQL CQDLPPCQPG CYCPKGLLEQ AGGCIPPEEC NCWHTSAAGA GMTLAPGDRL
4510 4520 4530 4540 4550 4560
QLGCKECECR RGELHCTSQG CQGLLPLSEW SEWSPCGPCL PPSALAPASR TALEEHWLRD
4570 4580 4590 4600 4610 4620
PTGLSPTLAP LLASEQHRHR LCLDPATGRP WTGAPHLCTA PLSQQRLCPD PGACPDSCQW
4630 4640 4650 4660 4670 4680
SLWGPWSPCQ VPCSGGFRLR WREAEALCGG GCREPWAQES CNGGPCPESC EAQDTVFTLD
4690 4700 4710 4720 4730 4740
CANQCPHSCA DLWDRVQCLQ GPCRPGCRCP PGQLVQDGRC VPISSCRCGL PSANASWELA
4750 4760 4770 4780 4790 4800
PAQAVQLDCQ NCTCVNESLV CPHQECPVLG PWSAWSSCSA PCGGGTMERH RTCEGGPGVA
4810 4820 4830 4840 4850 4860
PCQAQDTEQR QECNLQPCPE CPPGQVLSAC ATSCPCLCWH LQPGAICVQE PCQPGCGCPG
4870 4880 4890 4900 4910 4920
GQLLHNGTCV PPTACPCTQH SLPWGLTLTL EEQAQELPPG TVLTRNCTRC VCHGGAFSCS
4930 4940 4950 4960 4970 4980
LVDCQVPPGE TWQQVAPGEL GLCEQTCLEM NATKTQSNCS SARASGCVCQ PGHFRSQAGP
4990 5000 5010 5020 5030 5040
CVPEDHCECW HLGRPHLPGS EWQEACESCL CLSGRPVCTQ HCSPLTCAQG EEMVLEPGSC
5050 5060 5070 5080 5090 5100
CPSCRREAPE EQSPSCQLLT ELRNFTKGTC YLDQVEVSYC SGYCPSSTHV MPEEPYLQSQ
5110 5120 5130 5140 5150
CDCCSYRLDP ESPVRILNLR CLGGHTEPVV LPVIHSCQCS SCQGGDFSKR
10 20 30 40 50 60
MLLPALLFGM AWALADGRWC EWTETIRVEE EVAPRQEDLV PCASLDHYSR LGWRLDLPWS
70 80 90 100 110 120
GRSGLTRSPA PGLCPIYKPP ETRPAKWNRT VRTCCPGWGG AHCTEALAKA SPEGHCFAMW
130 140 150 160 170 180
QCQLQAGSAN ASAGSLEECC ARPWGQSWWD GSSQACRSCS SRHLPGSASS PALLQPLAGA
190 200 210 220 230 240
VGQLWSQHQR PSATCASWSG FHYRTFDGRH YHFLGRCTYL LAGAADSTWA VHLTPGDRCP
250 260 270 280 290 300
QPGHCQRVTM GPEEVLIQAG NVSVKGQLVP EGQSWLLHGL SLQWLGDWLV LSGGLGVVVR
310 320 330 340 350 360
LDRTGSISIS VDHELWGQTQ GLCGLYNGWP EDDFMEPGGG LAMLAATFGN SWRLPGSESG
370 380 390 400 410 420
CLDAVEVAQG CDSPLGLIDA DVEPGHLRAE AQDVCHQLLE GPFGQCHAQV SPAEYHEACL
430 440 450 460 470 480
FAYCAGAMAG SGQEGRQQAV CATFASYVQA CARRHIHIRW RKPGFCERLC PGGQLYSDCV
490 500 510 520 530 540
SLCPPSCEAV GQGEEESCRE ECVSGCECPR GLFWNGTLCV PAAHCPCYYC RQRYVPGDTV
550 560 570 580 590 600
RQLCNPCVCR DGRWHCAQAL CPAECAVGGD GHYLTFDGRS YSFWGGQGCR YSLVQDYVKG
610 620 630 640 650 660
QLLILLEHGA CDAGSCLHAI SVSLEDTHIQ LRDSGAVLVN GQDVGLPWIG AEGLSVRRAS
670 680 690 700 710 720
SAFLLLRWPG AQVLWGLSDP VAYITLDPRH AHQVQGLCGT FTQNQQDDFL TPAGDVETSI
730 740 750 760 770 780
AAFASKFQVA GKGRCPSEDS ALLSPCTTHS QRHAFAEAAC AILHSSVFQE CHRLVDKEPF
790 800 810 820 830 840
YLRCLAAVCG CDPGSDCLCP VLSAYARRCA QEGASPPWRN QTLCPVMCPG GQEYRECAPA
850 860 870 880 890 900
CGQHCGKPED CGELGSCVAG CNCPLGLLWD PEGQCVPPSL CPCQLGARRY APGSATMKEC
910 920 930 940 950 960
NRCICQERGL WNCTARHCPS QAFCPRELVY APGACLLTCD SPSANHSCPA GSTDGCVCPP
970 980 990 1000 1010 1020
GTVLLDERCV PPDLCPCRHS GQWYLPNATI QEDCNVCVCR GRQWHCTGQR RSGRCQASGA
1030 1040 1050 1060 1070 1080
PHYVTFDGLA FTYPGACEYL LVREASGLFT VSAQNLPCGA SGLTCTKALA VRLEGTVVHM
1090 1100 1110 1120 1130 1140
LRGRAVTVNG VSVTPPKVYT GPGLSLRRAG LFLLLSTHLG LTLLWDGGTR VLVQLSPQFR
1150 1160 1170 1180 1190 1200
GRVAGLCGDF DGDASNDLRS RQGVLEPTAE LAAHSWRLSP LCPEPGDLPH PCTMNTHRAG
1210 1220 1230 1240 1250 1260
WARARCGALL QPLFTLCHAE VPPQQHYEWC LYDACGCDSG GDCECLCSAI ATYADECARH
1270 1280 1290 1300 1310 1320
GHHVRWRSQE LCSLQCEGGQ VYEACGPTCP PTCHEQHPEP GWHCQVVACV EGCFCPEGTL
1330 1340 1350 1360 1370 1380
LHGGACLEPA SCPCEWGRNS FPPGSVLQKD CGNCTCQEGQ WHCGGDGGHC EELVPACAEG
1390 1400 1410 1420 1430 1440
EALCQENGHC VPHGWLCDNQ DDCGDGSDEE GCAAPGCGEG QMTCSSGHCL PLALLCDRQD
1450 1460 1470 1480 1490 1500
DCGDGTDEPS YPCPQGLLAC ADGRCLPPAL LCDGHPDCLD AADEESCLGQ VTCVPGEVSC
1510 1520 1530 1540 1550 1560
VDGTCLGAIQ LCDGVWDCPD GADEGPGHCP LPSLPTPPAS TLPGPSPGSL DTASSPLASA
1570 1580 1590 1600 1610 1620
SPAPPCGPFE FRCGSGECTP RGWRCDQEED CADGSDERGC GGPCAPHHAP CARGPHCVSP
1630 1640 1650 1660 1670 1680
EQLCDGVRQC PDGSDEGPDA CGGLPALGGP NRTGLPCPEY TCPNGTCIGF QLVCDGQPDC
1690 1700 1710 1720 1730 1740
GRPGQVGPSP EEQGCGAWGP WSPWGPCSRT CGPWGQGRSR RCSPLGLLVL QNCPGPEHQS
1750 1760 1770 1780 1790 1800
QACFTAACPV DGEWSTWSPW SVCSEPCRGT MTRQRQCHSP QNGGRTCAAL PGGLHSTRQT
1810 1820 1830 1840 1850 1860
KPCPQDGCPN ATCSGELMFQ PCAPCPLTCD DISGQVTCPP DWPCGSPGCW CPEGQVLGSE
1870 1880 1890 1900 1910 1920
GWCVWPRQCP CLVDGARYWP GQRIKADCQL CICQDGRPRR CRLNPDCAVD CGWSSWSPWA
1930 1940 1950 1960 1970 1980
KCLGPCGSQS IQWSFRSSNN PRPSGRGRQC RGIHRKARRC QTEPCEGCEH QGQVHRVGER
1990 2000 2010 2020 2030 2040
WHGGPCRVCQ CLHNLTAHCS PYCPLGSCPQ GWVLVEGTGE SCCHCALPGE NQTVQPMATP
2050 2060 2070 2080 2090 2100
AAAPAPSPQI RFPLATYILP PSGDPCYSPL GLAGLAEGSL HASSQQLEHP TQAALLGAPT
2110 2120 2130 2140 2150 2160
QGPSPQGWHA GGDAYAKWHT RPHYLQLDLL QPRNLTGILV PETGSSNAYA SSFSLQFSSN
2170 2180 2190 2200 2210 2220
GLHWHDYRDL LPGILPLPKL FPRNWDDLDP AVWTFGRMVQ ARFVRVWPHD VHHSDVPLQV
2230 2240 2250 2260 2270 2280
ELLGCEPGSP PAPLCPGVGL RCASGECVLR GGPCDGVLDC EDGSDEEGCV LLPEGTGRFH
2290 2300 2310 2320 2330 2340
STAKTLALSS AQPGQLLHWP REGLAETEHW PPGQESPTSP TETRPVSPGP ASGVPHHGES
2350 2360 2370 2380 2390 2400
VQMVTTTPIP QMEARTLPPG MAAVTVVPPH PVTPATPAGQ SVAPGPFPPV QCGPGQTPCE
2410 2420 2430 2440 2450 2460
VLGCVEQAQV CDGREDCLDG SDERHCARNL LMWLPSLPAL WAASTVPFMM PTMALPGLPA
2470 2480 2490 2500 2510 2520
SRALCSPSQL SCGSGECLSA ERRCDLRPDC QDGSDEDGCV DCVLAPWSVW SSCSRSCGLG
2530 2540 2550 2560 2570 2580
LTFQRQELLR PPLPGGSCPR DRFRSQSCFV QACPVAGAWA MWEAWGPCSV SCGGGHQSRQ
2590 2600 2610 2620 2630 2640
RSCVDPPPKN GGAPCPGASQ ERAPCGLQPC SGGTDCELGR VYVSADLCQK GLVPPCPPSC
2650 2660 2670 2680 2690 2700
LDPKANRSCS GHCVEGCRCP PGLLLHDTRC LPLSECPCLV GEELKWPGVS FLLGNCSQCV
2710 2720 2730 2740 2750 2760
CEKGELLCQP GGCPLPCGWS AWSSWAPCDR SCGSGVRARF RSPSNPPAAW GGAPCEGDRQ
2770 2780 2790 2800 2810 2820
ELQGCHTVCG TEVFGWTPWT SWSSCSQSCL APGGGPGWRS RSRLCPSPGD SSCPGDATQE
2830 2840 2850 2860 2870 2880
EPCSPPVCPV PSIWGLWAPW STCSAPCDGG IQTRGRSCSS LAPGDTTCPG PHSQTRDCNT
2890 2900 2910 2920 2930 2940
QPCTAQCPEN MLFRSAEQCH QEGGPCPRLC LTQGPGIECT GFCAPGCTCP PGLFLHNASC
2950 2960 2970 2980 2990 3000
LPRSQCPCQL HGQLYASGAM ARLDSCNNCT CVSGKMACTS ERCPVACGWS PWTLWSLCSC
3010 3020 3030 3040 3050 3060
SCNVGIRRRF RAGTAPPAAF GGAECQGPTM EAEFCSLRPC PGPGGEWGPW SPCSVPCGGG
3070 3080 3090 3100 3110 3120
YRNRTRGSSR SLMEFSTCGL QPCAGPVPGM CPRDKQWLDC AQGPASCAEL SAPRGTNQTC
3130 3140 3150 3160 3170 3180
HPGCHCPSGM LLLNNVCVPT QDCPCAHEGH LYPPGSTVVR PCENCSCVSG LIANCSSWPC
3190 3200 3210 3220 3230 3240
AEGEPTWSPW TPWSQCSASC GPARCHRHRF CARSPSAVPS TVAPLPLPAT PTPLCSGPEA
3250 3260 3270 3280 3290 3300
EEEPCLLQGC DRAGGWGPWG PWSHCSRSCG GGLRSRTRAC DQPPPQGLGD YCEGPRAQGE
3310 3320 3330 3340 3350 3360
VCQALPCPVT NCTAIEGAEY SPCGPPCPRS CDDLVHCVWR CQPGCYCPPG QVLSSNGAIC
3370 3380 3390 3400 3410 3420
VQPGHCSCLD LLTGQRHHPG ARLARPDGCN HCTCLEGRLN CTDLPCPVPG GWCPWSEWTM
3430 3440 3450 3460 3470 3480
CSQPCRGQTR SRSRACACPT PQHGGAPCTG EAGEAGAQHQ REACPSYATC PVDGAWGPWG
3490 3500 3510 3520 3530 3540
PWSPCDMCLG QSHRSRACSR PPTPEGGRPC PGNHTQSRPC QENSTQCTDC GGGQSLHPCG
3550 3560 3570 3580 3590 3600
QPCPRSCQDL SPGSVCQPGS VGCQPTCGCP LGQLSQDGLC VPPAHCRCQY QPGAMGIPEN
3610 3620 3630 3640 3650 3660
QSRSAGSRFS SWESLEPGEV VTGPCDNCTC VAGILQCQEV PDCPDPGVWS SWGPWEDCSV
3670 3680 3690 3700 3710 3720
SCGGGEQLRS RRCARPPCPG PARQSRTCST QVCREAGCPA GRLYRECQPG EGCPFSCAHV
3730 3740 3750 3760 3770 3780
TQQVGCFSEG CEEGCHCPEG TFQHRLACVQ ECPCVLTAWL LQELGATIGD PGQPLGPGDE
3790 3800 3810 3820 3830 3840
LDSGQTLRTS CGNCSCAHGK LSCSLDDCFE ADGGFGPWSP WGPCSRSCGG LGTRTRSRQC
3850 3860 3870 3880 3890 3900
VLTMPTLSGQ GCRGPRQDLE YCPSPDCPGA EGSTVEPVTG LPGGWGPWSS WSPCSRSCTD
3910 3920 3930 3940 3950 3960
PARPAWRSRT RLCLANCTMG DPLQERPCNL PSCTELPVCP GPGCGAGNCS WTSWAPWEPC
3970 3980 3990 4000 4010 4020
SRSCGVGQQR RLRAYRPPGP GGHWCPNILT AYQERRFCNL RACPVPGGWS RWSPWSWCDR
4030 4040 4050 4060 4070 4080
SCGGGQSLRS RSCSSPPSKN GGAPCAGERH QARLCNPMPC EAGCPAGMEV VTCANRCPRR
4090 4100 4110 4120 4130 4140
CSDLQEGIVC QDDQVCQKGC RCPKGSLEQD GGCVPIGHCD CTDAQGHSWA PGSQHQDACN
4150 4160 4170 4180 4190 4200
NCSCQAGQLS CTAQPCPPPT HCAWSHWSAW SPCSHSCGPR GQQSRFRSST SGSWAPECRE
4210 4220 4230 4240 4250 4260
EQSQSQPCPQ PSCPPLCLQG TRSRTLGDSW LQGECQRCSC TPEGVICEDT ECAVPEAWTL
4270 4280 4290 4300 4310 4320
WSSWSDCPVS CGGGNQVRTR ACRAAAPHHR SPPCLGPDTQ TRQQPCPGLL EACSWGPWGP
4330 4340 4350 4360 4370 4380
CSRSCGPGLA SRSGSCPCLM AKADPTCNST FLHLDTQGCY SGPCPEECVW SSWSSWTRCS
4390 4400 4410 4420 4430 4440
CRVLVQQRYR HQGPASRGAR AGAPCTRLDG HFRPCLISNC SEDSCTPPFE FHACGSPCAG
4450 4460 4470 4480 4490 4500
LCATHLSHQL CQDLPPCQPG CYCPKGLLEQ AGGCIPPEEC NCWHTSAAGA GMTLAPGDRL
4510 4520 4530 4540 4550 4560
QLGCKECECR RGELHCTSQG CQGLLPLSEW SEWSPCGPCL PPSALAPASR TALEEHWLRD
4570 4580 4590 4600 4610 4620
PTGLSPTLAP LLASEQHRHR LCLDPATGRP WTGAPHLCTA PLSQQRLCPD PGACPDSCQW
4630 4640 4650 4660 4670 4680
SLWGPWSPCQ VPCSGGFRLR WREAEALCGG GCREPWAQES CNGGPCPESC EAQDTVFTLD
4690 4700 4710 4720 4730 4740
CANQCPHSCA DLWDRVQCLQ GPCRPGCRCP PGQLVQDGRC VPISSCRCGL PSANASWELA
4750 4760 4770 4780 4790 4800
PAQAVQLDCQ NCTCVNESLV CPHQECPVLG PWSAWSSCSA PCGGGTMERH RTCEGGPGVA
4810 4820 4830 4840 4850 4860
PCQAQDTEQR QECNLQPCPE CPPGQVLSAC ATSCPCLCWH LQPGAICVQE PCQPGCGCPG
4870 4880 4890 4900 4910 4920
GQLLHNGTCV PPTACPCTQH SLPWGLTLTL EEQAQELPPG TVLTRNCTRC VCHGGAFSCS
4930 4940 4950 4960 4970 4980
LVDCQVPPGE TWQQVAPGEL GLCEQTCLEM NATKTQSNCS SARASGCVCQ PGHFRSQAGP
4990 5000 5010 5020 5030 5040
CVPEDHCECW HLGRPHLPGS EWQEACESCL CLSGRPVCTQ HCSPLTCAQG EEMVLEPGSC
5050 5060 5070 5080 5090 5100
CPSCRREAPE EQSPSCQLLT ELRNFTKGTC YLDQVEVSYC SGYCPSSTHV MPEEPYLQSQ
5110 5120 5130 5140 5150
CDCCSYRLDP ESPVRILNLR CLGGHTEPVV LPVIHSCQCS SCQGGDFSKR
Protein Neighborhood
Domains & Features
3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| A2VEC9-18-unknown | RWCEWT... | 18 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| A2VEC9-2043- | APAPSP... | 2043 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
| A2VEC9-2043-unknown | APAPSP... | 2043 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt178502 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...QGGDFS | 5147 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|