TopFIND 4.0

A6ND01: Sperm-egg fusion protein Juno {ECO:0000305}

General Information

Protein names
- Sperm-egg fusion protein Juno {ECO:0000305}
- Folate receptor 4
- Folate receptor delta {ECO:0000250|UniProtKB:Q9EQF4}
- FR-delta {ECO:0000250|UniProtKB:Q9EQF4}
- IZUMO1 receptor protein JUNO {ECO:0000303|PubMed:24739963}
Gene names FOLR4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID A6ND01

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MACWWPLLLE LWTVMPTWAG DELLNICMNA KHHKRVPSPE DKLYEECIPW KDNACCTLTT 
        70         80         90        100        110        120 
SWEAHLDVSP LYNFSLFHCG LLMPGCRKHF IQAICFYECS PNLGPWIQPV GSLGWEVAPS 
       130        140        150        160        170        180 
GQGERVVNVP LCQEDCEEWW EDCRMSYTCK SNWRGGWDWS QGKNRCPKGA QCLPFSHYFP 
       190        200        210        220        230        240 
TPADLCEKTW SNSFKASPER RNSGRCLQKW FEPAQGNPNV AVARLFASSA PSWELSYTIM 
       250    
VCSLFLPFLS 

Isoforms

- Isoform 2 of Sperm-egg fusion protein Juno

Sequence View

        10         20         30         40         50         60 
MACWWPLLLE LWTVMPTWAG DELLNICMNA KHHKRVPSPE DKLYEECIPW KDNACCTLTT 
        70         80         90        100        110        120 
SWEAHLDVSP LYNFSLFHCG LLMPGCRKHF IQAICFYECS PNLGPWIQPV GSLGWEVAPS 
       130        140        150        160        170        180 
GQGERVVNVP LCQEDCEEWW EDCRMSYTCK SNWRGGWDWS QGKNRCPKGA QCLPFSHYFP 
       190        200        210        220        230        240 
TPADLCEKTW SNSFKASPER RNSGRCLQKW FEPAQGNPNV AVARLFASSA PSWELSYTIM 
       250    
VCSLFLPFLS 



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    A6ND01-1-unknown MACWWP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78349
    A6ND01-20-unknown GDELLN... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    A6ND01-20-unknown GDELLN... 20 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112538

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)