A8K2U0: Alpha-2-macroglobulin-like protein 1

General Information

Protein names	- Alpha-2-macroglobulin-like protein 1 - C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9
Gene names	A2ML1
Organism	Homo sapiens
Protease Family
Protease ID	I39.007
Chromosome location
UniProt ID	A8K2U0

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MWAQLLLGML ALSPAIAEEL PNYLVTLPAR LNFPSVQKVC LDLSPGYSDV KFTVTLETKD
        70         80         90        100        110        120
KTQKLLEYSG LKKRHLHCIS FLVPPPAGGT EEVATIRVSG VGNNISFEEK KKVLIQRQGN
       130        140        150        160        170        180
GTFVQTDKPL YTPGQQVYFR IVTMDSNFVP VNDKYSMVEL QDPNSNRIAQ WLEVVPEQGI
       190        200        210        220        230        240
VDLSFQLAPE AMLGTYTVAV AEGKTFGTFS VEEYVLPKFK VEVVEPKELS TVQESFLVKI
       250        260        270        280        290        300
CCRYTYGKPM LGAVQVSVCQ KANTYWYREV EREQLPDKCR NLSGQTDKTG CFSAPVDMAT
       310        320        330        340        350        360
FDLIGYAYSH QINIVATVVE EGTGVEANAT QNIYISPQMG SMTFEDTSNF YHPNFPFSGK
       370        380        390        400        410        420
IRVRGHDDSF LKNHLVFLVI YGTNGTFNQT LVTDNNGLAP FTLETSGWNG TDVSLEGKFQ
       430        440        450        460        470        480
MEDLVYNPEQ VPRYYQNAYL HLRPFYSTTR SFLGIHRLNG PLKCGQPQEV LVDYYIDPAD
       490        500        510        520        530        540
ASPDQEISFS YYLIGKGSLV MEGQKHLNSK KKGLKASFSL SLTFTSRLAP DPSLVIYAIF
       550        560        570        580        590        600
PSGGVVADKI QFSVEMCFDN QVSLGFSPSQ QLPGAEVELQ LQAAPGSLCA LRAVDESVLL
       610        620        630        640        650        660
LRPDRELSNR SVYGMFPFWY GHYPYQVAEY DQCPVSGPWD FPQPLIDPMP QGHSSQRSII
       670        680        690        700        710        720
WRPSFSEGTD LFSFFRDVGL KILSNAKIKK PVDCSHRSPE YSTAMGAGGG HPEAFESSTP
       730        740        750        760        770        780
LHQAEDSQVR QYFPETWLWD LFPIGNSGKE AVHVTVPDAI TEWKAMSFCT SQSRGFGLSP
       790        800        810        820        830        840
TVGLTAFKPF FVDLTLPYSV VRGESFRLTA TIFNYLKDCI RVQTDLAKSH EYQLESWADS
       850        860        870        880        890        900
QTSSCLCADD AKTHHWNITA VKLGHINFTI STKILDSNEP CGGQKGFVPQ KGRSDTLIKP
       910        920        930        940        950        960
VLVKPEGVLV EKTHSSLLCP KGKVASESVS LELPVDIVPD STKAYVTVLG DIMGTALQNL
       970        980        990       1000       1010       1020
DGLVQMPSGC GEQNMVLFAP IIYVLQYLEK AGLLTEEIRS RAVGFLEIGY QKELMYKHSN
      1030       1040       1050       1060       1070       1080
GSYSAFGERD GNGNTWLTAF VTKCFGQAQK FIFIDPKNIQ DALKWMAGNQ LPSGCYANVG
      1090       1100       1110       1120       1130       1140
NLLHTAMKGG VDDEVSLTAY VTAALLEMGK DVDDPMVSQG LRCLKNSATS TTNLYTQALL
      1150       1160       1170       1180       1190       1200
AYIFSLAGEM DIRNILLKQL DQQAIISGES IYWSQKPTPS SNASPWSEPA AVDVELTAYA
      1210       1220       1230       1240       1250       1260
LLAQLTKPSL TQKEIAKATS IVAWLAKQHN AYGGFSSTQD TVVALQALAK YATTAYMPSE
      1270       1280       1290       1300       1310       1320
EINLVVKSTE NFQRTFNIQS VNRLVFQQDT LPNVPGMYTL EASGQGCVYV QTVLRYNILP
      1330       1340       1350       1360       1370       1380
PTNMKTFSLS VEIGKARCEQ PTSPRSLTLT IHTSYVGSRS SSNMAIVEVK MLSGFSPMEG
      1390       1400       1410       1420       1430       1440
TNQLLLQQPL VKKVEFGTDT LNIYLDELIK NTQTYTFTIS QSVLVTNLKP ATIKVYDYYL
      1450
PDEQATIQYS DPCE

Isoforms

- Isoform 2 of Alpha-2-macroglobulin-like protein 1

Sequence View

        10         20         30         40         50         60
MWAQLLLGML ALSPAIAEEL PNYLVTLPAR LNFPSVQKVC LDLSPGYSDV KFTVTLETKD
        70         80         90        100        110        120
KTQKLLEYSG LKKRHLHCIS FLVPPPAGGT EEVATIRVSG VGNNISFEEK KKVLIQRQGN
       130        140        150        160        170        180
GTFVQTDKPL YTPGQQVYFR IVTMDSNFVP VNDKYSMVEL QDPNSNRIAQ WLEVVPEQGI
       190        200        210        220        230        240
VDLSFQLAPE AMLGTYTVAV AEGKTFGTFS VEEYVLPKFK VEVVEPKELS TVQESFLVKI
       250        260        270        280        290        300
CCRYTYGKPM LGAVQVSVCQ KANTYWYREV EREQLPDKCR NLSGQTDKTG CFSAPVDMAT
       310        320        330        340        350        360
FDLIGYAYSH QINIVATVVE EGTGVEANAT QNIYISPQMG SMTFEDTSNF YHPNFPFSGK
       370        380        390        400        410        420
IRVRGHDDSF LKNHLVFLVI YGTNGTFNQT LVTDNNGLAP FTLETSGWNG TDVSLEGKFQ
       430        440        450        460        470        480
MEDLVYNPEQ VPRYYQNAYL HLRPFYSTTR SFLGIHRLNG PLKCGQPQEV LVDYYIDPAD
       490        500        510        520        530        540
ASPDQEISFS YYLIGKGSLV MEGQKHLNSK KKGLKASFSL SLTFTSRLAP DPSLVIYAIF
       550        560        570        580        590        600
PSGGVVADKI QFSVEMCFDN QVSLGFSPSQ QLPGAEVELQ LQAAPGSLCA LRAVDESVLL
       610        620        630        640        650        660
LRPDRELSNR SVYGMFPFWY GHYPYQVAEY DQCPVSGPWD FPQPLIDPMP QGHSSQRSII
       670        680        690        700        710        720
WRPSFSEGTD LFSFFRDVGL KILSNAKIKK PVDCSHRSPE YSTAMGAGGG HPEAFESSTP
       730        740        750        760        770        780
LHQAEDSQVR QYFPETWLWD LFPIGNSGKE AVHVTVPDAI TEWKAMSFCT SQSRGFGLSP
       790        800        810        820        830        840
TVGLTAFKPF FVDLTLPYSV VRGESFRLTA TIFNYLKDCI RVQTDLAKSH EYQLESWADS
       850        860        870        880        890        900
QTSSCLCADD AKTHHWNITA VKLGHINFTI STKILDSNEP CGGQKGFVPQ KGRSDTLIKP
       910        920        930        940        950        960
VLVKPEGVLV EKTHSSLLCP KGKVASESVS LELPVDIVPD STKAYVTVLG DIMGTALQNL
       970        980        990       1000       1010       1020
DGLVQMPSGC GEQNMVLFAP IIYVLQYLEK AGLLTEEIRS RAVGFLEIGY QKELMYKHSN
      1030       1040       1050       1060       1070       1080
GSYSAFGERD GNGNTWLTAF VTKCFGQAQK FIFIDPKNIQ DALKWMAGNQ LPSGCYANVG
      1090       1100       1110       1120       1130       1140
NLLHTAMKGG VDDEVSLTAY VTAALLEMGK DVDDPMVSQG LRCLKNSATS TTNLYTQALL
      1150       1160       1170       1180       1190       1200
AYIFSLAGEM DIRNILLKQL DQQAIISGES IYWSQKPTPS SNASPWSEPA AVDVELTAYA
      1210       1220       1230       1240       1250       1260
LLAQLTKPSL TQKEIAKATS IVAWLAKQHN AYGGFSSTQD TVVALQALAK YATTAYMPSE
      1270       1280       1290       1300       1310       1320
EINLVVKSTE NFQRTFNIQS VNRLVFQQDT LPNVPGMYTL EASGQGCVYV QTVLRYNILP
      1330       1340       1350       1360       1370       1380
PTNMKTFSLS VEIGKARCEQ PTSPRSLTLT IHTSYVGSRS SSNMAIVEVK MLSGFSPMEG
      1390       1400       1410       1420       1430       1440
TNQLLLQQPL VKKVEFGTDT LNIYLDELIK NTQTYTFTIS QSVLVTNLKP ATIKVYDYYL
      1450
PDEQATIQYS DPCE

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
A8K2U0-18-unknown	EELPNY...	18		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
A8K2U0-451-unknown	SFLGIH...	451		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000443174

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FTSRLA	528	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440662
...EGTDLF	671	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440057
...SDPCE	1454	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

A8K2U0: Alpha-2-macroglobulin-like protein 1

General Information

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates