TopFIND 4.0

A8MQ27: E3 ubiquitin-protein ligase NEURL1B

General Information

Protein names
- E3 ubiquitin-protein ligase NEURL1B
- 2.3.2.27
- Neuralized-2
- NEUR2
- Neuralized-like protein 1B
- Neuralized-like protein 3
- RING-type E3 ubiquitin transferase NEURL1B {ECO:0000305}
Gene names NEURL1B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID A8MQ27

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGNTVHRTLP DPSPPARLLA TRPCCGPGPE RRPVLGEAPR FHAQAKGKNV RLDGHSRRAT 
        70         80         90        100        110        120 
RRNSFCNGVT FTQRPIRLYE QVRLRLVAVR PGWSGALRFG FTAHDPSLMS AQDIPKYACP 
       130        140        150        160        170        180 
DLVTRPGYWA KALPENLALR DTVLAYWADR HGRVFYSVND GEPVLFHCGV AVGGPLWALI 
       190        200        210        220        230        240 
DVYGITDEVQ LLESAFADTL TPARLSQARF SACLPPSSHD AANFDNNELE NNQVVAKLGH 
       250        260        270        280        290        300 
LALGRAPGPP PADAAAAAIP CGPRERPRPA SSPALLEADL RFHATRGPDV SLSADRKVAC 
       310        320        330        340        350        360 
APRPDGGRTL VFSERPLRPG ESLFVEVGRP GLAAPGALAF GITSCDPGVL RPNELPADPD 
       370        380        390        400        410        420 
ALLDRKEYWV VARAGPVPSG GDALSFTLRP GGDVLLGING RPRGRLLCVD TTQALWAFFA 
       430        440        450        460        470        480 
VRGGVAGQLR LLGTLQSSPA TTTPSGSLSG SQDDSDSDMT FSVNQSSSAS ESSLVTAPSS 
       490        500        510        520        530        540 
PLSPPVSPVF SPPEPAGIKN GECTVCFDGE VDTVIYTCGH MCLCHSCGLR LKRQARACCP 
       550    
ICRRPIKDVI KIYRP

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase NEURL1B - Isoform 3 of E3 ubiquitin-protein ligase NEURL1B

Sequence View

        10         20         30         40         50         60 
MGNTVHRTLP DPSPPARLLA TRPCCGPGPE RRPVLGEAPR FHAQAKGKNV RLDGHSRRAT 
        70         80         90        100        110        120 
RRNSFCNGVT FTQRPIRLYE QVRLRLVAVR PGWSGALRFG FTAHDPSLMS AQDIPKYACP 
       130        140        150        160        170        180 
DLVTRPGYWA KALPENLALR DTVLAYWADR HGRVFYSVND GEPVLFHCGV AVGGPLWALI 
       190        200        210        220        230        240 
DVYGITDEVQ LLESAFADTL TPARLSQARF SACLPPSSHD AANFDNNELE NNQVVAKLGH 
       250        260        270        280        290        300 
LALGRAPGPP PADAAAAAIP CGPRERPRPA SSPALLEADL RFHATRGPDV SLSADRKVAC 
       310        320        330        340        350        360 
APRPDGGRTL VFSERPLRPG ESLFVEVGRP GLAAPGALAF GITSCDPGVL RPNELPADPD 
       370        380        390        400        410        420 
ALLDRKEYWV VARAGPVPSG GDALSFTLRP GGDVLLGING RPRGRLLCVD TTQALWAFFA 
       430        440        450        460        470        480 
VRGGVAGQLR LLGTLQSSPA TTTPSGSLSG SQDDSDSDMT FSVNQSSSAS ESSLVTAPSS 
       490        500        510        520        530        540 
PLSPPVSPVF SPPEPAGIKN GECTVCFDGE VDTVIYTCGH MCLCHSCGLR LKRQARACCP 
       550    
ICRRPIKDVI KIYRP         10         20         30         40         50         60 
MGNTVHRTLP DPSPPARLLA TRPCCGPGPE RRPVLGEAPR FHAQAKGKNV RLDGHSRRAT 
        70         80         90        100        110        120 
RRNSFCNGVT FTQRPIRLYE QVRLRLVAVR PGWSGALRFG FTAHDPSLMS AQDIPKYACP 
       130        140        150        160        170        180 
DLVTRPGYWA KALPENLALR DTVLAYWADR HGRVFYSVND GEPVLFHCGV AVGGPLWALI 
       190        200        210        220        230        240 
DVYGITDEVQ LLESAFADTL TPARLSQARF SACLPPSSHD AANFDNNELE NNQVVAKLGH 
       250        260        270        280        290        300 
LALGRAPGPP PADAAAAAIP CGPRERPRPA SSPALLEADL RFHATRGPDV SLSADRKVAC 
       310        320        330        340        350        360 
APRPDGGRTL VFSERPLRPG ESLFVEVGRP GLAAPGALAF GITSCDPGVL RPNELPADPD 
       370        380        390        400        410        420 
ALLDRKEYWV VARAGPVPSG GDALSFTLRP GGDVLLGING RPRGRLLCVD TTQALWAFFA 
       430        440        450        460        470        480 
VRGGVAGQLR LLGTLQSSPA TTTPSGSLSG SQDDSDSDMT FSVNQSSSAS ESSLVTAPSS 
       490        500        510        520        530        540 
PLSPPVSPVF SPPEPAGIKN GECTVCFDGE VDTVIYTCGH MCLCHSCGLR LKRQARACCP 
       550    
ICRRPIKDVI KIYRP



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    A8MQ27-1-unknown MGNTVH... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    A8MQ27-1-unknown MGNTVH... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82638

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)