TopFIND 4.0

A8MV23: Serpin E3

General Information

Protein names
- Serpin E3
Gene names SERPINE3
Organism Homo sapiens
Protease Family
Protease ID I04.972
Chromosome location
UniProt ID A8MV23

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPPFLITLFL FHSCCLRANG HLREGMTLLK TEFALHLYQS VAACRNETNF VISPAGVSLP 
        70         80         90        100        110        120 
LEILQFGAEG STGQQLADAL GYTVHDKRVK DFLHAVYATL PTSSQGTEME LACSLFVQVG 
       130        140        150        160        170        180 
TPLSPCFVEH VSWWANSSLE PADLSEPNST AIQTSEGASR ETAGGGPSEG PGGWPWEQVS 
       190        200        210        220        230        240 
AAFAQLVLVS TMSFQGTWRK RFSSTDTQIL PFTCAYGLVL QVPMMHQTTE VNYGQFQDTA 
       250        260        270        280        290        300 
GHQVGVLELP YLGSAVSLFL VLPRDKDTPL SHIEPHLTAS TIHLWTTSLR RARMDVFLPR 
       310        320        330        340        350        360 
FRIQNQFNLK SILNSWGVTD LFDPLKANLK GISGQDGFYV SEAIHKAKIE VLEEGTKASG 
       370        380        390        400        410        420 
ATALLLLKRS RIPIFKADRP FIYFLREPNT GITVFFDRIQ IIYQCLSSNK GSFVHYPLKN 
   
KHSF

Isoforms

- Isoform 2 of Serpin E3

Sequence View

        10         20         30         40         50         60 
MPPFLITLFL FHSCCLRANG HLREGMTLLK TEFALHLYQS VAACRNETNF VISPAGVSLP 
        70         80         90        100        110        120 
LEILQFGAEG STGQQLADAL GYTVHDKRVK DFLHAVYATL PTSSQGTEME LACSLFVQVG 
       130        140        150        160        170        180 
TPLSPCFVEH VSWWANSSLE PADLSEPNST AIQTSEGASR ETAGGGPSEG PGGWPWEQVS 
       190        200        210        220        230        240 
AAFAQLVLVS TMSFQGTWRK RFSSTDTQIL PFTCAYGLVL QVPMMHQTTE VNYGQFQDTA 
       250        260        270        280        290        300 
GHQVGVLELP YLGSAVSLFL VLPRDKDTPL SHIEPHLTAS TIHLWTTSLR RARMDVFLPR 
       310        320        330        340        350        360 
FRIQNQFNLK SILNSWGVTD LFDPLKANLK GISGQDGFYV SEAIHKAKIE VLEEGTKASG 
       370        380        390        400        410        420 
ATALLLLKRS RIPIFKADRP FIYFLREPNT GITVFFDRIQ IIYQCLSSNK GSFVHYPLKN 
   
KHSF



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    A8MV23-1-unknown MPPFLI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89324
    A8MV23-21-unknown HLREGM... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    A8MV23-21-unknown HLREGM... 21 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112630

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NKHSF 424 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)