TopFIND 4.0

B1AUH1: Receptor-type tyrosine-protein phosphatase U

General Information

Protein names
- Receptor-type tyrosine-protein phosphatase U
- R-PTP-U
- 3.1.3.48
- Ftp-1
- Pancreatic carcinoma phosphatase 2
- PCP-2
- Protein-tyrosine phosphatase-lamda
- PTP-lambda
- PTPlambda
- Receptor-type protein-tyrosine phosphatase psi
- R-PTP-psi
Gene names Ptpru
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID B1AUH1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MARAQALVLA LTFQFCAPET ETPAAGCTFE EASDPVVPCE FSQAQYDDFQ WEQVRIHPGT 
        70         80         90        100        110        120 
RTPEDLPHGA YLMVNASQHA PGQRAHIIFQ TLSENDTHCV QFSYFLYSRD GHSPGTLGVY 
       130        140        150        160        170        180 
VRVNGGPLGS AVWNMTGSHG RQWHQAELAV STFWPNEYQV LFEALISPDH KGYIGLDDIL 
       190        200        210        220        230        240 
LFSYPCAKAP HFSRLGDVEV NAGQNASFQC MAAGRAAEAE HFFLQRQSGV LVPAAGVRHI 
       250        260        270        280        290        300 
SHRRFLATFP LASVGRSEQD LYRCVSQAPR GAGVSNFAEL IVKEPPTPIA PPQLLRAGPT 
       310        320        330        340        350        360 
YLIIQLNTNS IIGDGPIVRK EIEYRMARGP WAEVHAVNLQ TYKLWHLDPD TEYEISVLLT 
       370        380        390        400        410        420 
RPGDGGTGRP GPPLISRTKC AEPTRAPKGL AFAEIQARQL TLQWEPLGYN VTRCHTYAVS 
       430        440        450        460        470        480 
LCYRYTLGGS HNQTIRECVK MERGASRYTI KNLLPFRNIH VRLILTNPEG RKEGKEVTFQ 
       490        500        510        520        530        540 
TDEDVPGGIA AESLTFTPLE DMIFLKWEEP QEPNGLITQY EISYQSIESS DPAVNVPGPR 
       550        560        570        580        590        600 
RTISKLRNET YHVFSNLHPG TTYLFSVRAR TSKGFGQAAL TEITTNISAP SFDYADMPSP 
       610        620        630        640        650        660 
LGESENTITV LLRPAQGRGA PISVYQVVVE EERPRRLRRE PGAQDCFSVP LTFETALARG 
       670        680        690        700        710        720 
LVHYFGAELA ASSLLEAMPF TVGDNQTYRG FWNPPLEPRK AYLIYFQAAS HLKGETRLNC 
       730        740        750        760        770        780 
IRIARKAACK ESKRPLEVSQ RSEEMGLILG ICAGGLAVLI LLLGAIIVII RKGRDRYAYS 
       790        800        810        820        830        840 
YYPKPVNMTK ATVNYRQEKT HMMSAVDRSF TDQSTLQEDE RLGLSFMDAP GYSPRGDQRS 
       850        860        870        880        890        900 
GGVTEASSLL GGSPRRPCGR KGSPYHTGQL HPAVRVADLL QHINQMKTAE GYGFKQEYES 
       910        920        930        940        950        960 
FFEGWDATKK KDKLKGGRQE PVSAYDRHHV KLHPMLADPD ADYISANYID GYHRSNHFIA 
       970        980        990       1000       1010       1020 
TQGPKPEMIY DFWRMVWQEQ CASIVMITKL VEVGRVKCSR YWPEDSDMYG DIKITLVKTE 
      1030       1040       1050       1060       1070       1080 
TLAEYVVRTF ALERRGYSAR HEVRQFHFTA WPEHGVPYHA TGLLAFIRRV KASTPPDAGP 
      1090       1100       1110       1120       1130       1140 
IVIHCSAGTG RTGCYIVLDV MLDMAECEGV VDIYNCVKTL CSRRVNMIQT EEQYIFIHDA 
      1150       1160       1170       1180       1190       1200 
ILEACLCGET TIPVNEFKAT YREMIRIDPQ SNSSQLREEF QTLNSVTPPL DVEECSIALL 
      1210       1220       1230       1240       1250       1260 
PRNRDKNRSM DVLPPDRCLP FLISSDGDPN NYINAALTDS YTRSAAFIVT LHPLQSTTPD 
      1270       1280       1290       1300       1310       1320 
FWRLVYDYGC TSIVMLNQLN QSNSAWPCLQ YWPEPGRQQY GLMEVEFVSG TANEDLVSRV 
      1330       1340       1350       1360       1370       1380 
FRVQNSSRLQ EGHLLVRHFQ FLRWSAYRDT PDSRKAFLHL LAEVDKWQAE SGDGRTVVHC 
      1390       1400       1410       1420       1430       1440 
LNGGGRSGTF CACATVLEMI RCHSLVDVFF AAKTLRNYKP NMVETMDQYH FCYDVALEYL 
   
EALELR

Isoforms

- Isoform 2 of Receptor-type tyrosine-protein phosphatase U

Sequence View

        10         20         30         40         50         60 
MARAQALVLA LTFQFCAPET ETPAAGCTFE EASDPVVPCE FSQAQYDDFQ WEQVRIHPGT 
        70         80         90        100        110        120 
RTPEDLPHGA YLMVNASQHA PGQRAHIIFQ TLSENDTHCV QFSYFLYSRD GHSPGTLGVY 
       130        140        150        160        170        180 
VRVNGGPLGS AVWNMTGSHG RQWHQAELAV STFWPNEYQV LFEALISPDH KGYIGLDDIL 
       190        200        210        220        230        240 
LFSYPCAKAP HFSRLGDVEV NAGQNASFQC MAAGRAAEAE HFFLQRQSGV LVPAAGVRHI 
       250        260        270        280        290        300 
SHRRFLATFP LASVGRSEQD LYRCVSQAPR GAGVSNFAEL IVKEPPTPIA PPQLLRAGPT 
       310        320        330        340        350        360 
YLIIQLNTNS IIGDGPIVRK EIEYRMARGP WAEVHAVNLQ TYKLWHLDPD TEYEISVLLT 
       370        380        390        400        410        420 
RPGDGGTGRP GPPLISRTKC AEPTRAPKGL AFAEIQARQL TLQWEPLGYN VTRCHTYAVS 
       430        440        450        460        470        480 
LCYRYTLGGS HNQTIRECVK MERGASRYTI KNLLPFRNIH VRLILTNPEG RKEGKEVTFQ 
       490        500        510        520        530        540 
TDEDVPGGIA AESLTFTPLE DMIFLKWEEP QEPNGLITQY EISYQSIESS DPAVNVPGPR 
       550        560        570        580        590        600 
RTISKLRNET YHVFSNLHPG TTYLFSVRAR TSKGFGQAAL TEITTNISAP SFDYADMPSP 
       610        620        630        640        650        660 
LGESENTITV LLRPAQGRGA PISVYQVVVE EERPRRLRRE PGAQDCFSVP LTFETALARG 
       670        680        690        700        710        720 
LVHYFGAELA ASSLLEAMPF TVGDNQTYRG FWNPPLEPRK AYLIYFQAAS HLKGETRLNC 
       730        740        750        760        770        780 
IRIARKAACK ESKRPLEVSQ RSEEMGLILG ICAGGLAVLI LLLGAIIVII RKGRDRYAYS 
       790        800        810        820        830        840 
YYPKPVNMTK ATVNYRQEKT HMMSAVDRSF TDQSTLQEDE RLGLSFMDAP GYSPRGDQRS 
       850        860        870        880        890        900 
GGVTEASSLL GGSPRRPCGR KGSPYHTGQL HPAVRVADLL QHINQMKTAE GYGFKQEYES 
       910        920        930        940        950        960 
FFEGWDATKK KDKLKGGRQE PVSAYDRHHV KLHPMLADPD ADYISANYID GYHRSNHFIA 
       970        980        990       1000       1010       1020 
TQGPKPEMIY DFWRMVWQEQ CASIVMITKL VEVGRVKCSR YWPEDSDMYG DIKITLVKTE 
      1030       1040       1050       1060       1070       1080 
TLAEYVVRTF ALERRGYSAR HEVRQFHFTA WPEHGVPYHA TGLLAFIRRV KASTPPDAGP 
      1090       1100       1110       1120       1130       1140 
IVIHCSAGTG RTGCYIVLDV MLDMAECEGV VDIYNCVKTL CSRRVNMIQT EEQYIFIHDA 
      1150       1160       1170       1180       1190       1200 
ILEACLCGET TIPVNEFKAT YREMIRIDPQ SNSSQLREEF QTLNSVTPPL DVEECSIALL 
      1210       1220       1230       1240       1250       1260 
PRNRDKNRSM DVLPPDRCLP FLISSDGDPN NYINAALTDS YTRSAAFIVT LHPLQSTTPD 
      1270       1280       1290       1300       1310       1320 
FWRLVYDYGC TSIVMLNQLN QSNSAWPCLQ YWPEPGRQQY GLMEVEFVSG TANEDLVSRV 
      1330       1340       1350       1360       1370       1380 
FRVQNSSRLQ EGHLLVRHFQ FLRWSAYRDT PDSRKAFLHL LAEVDKWQAE SGDGRTVVHC 
      1390       1400       1410       1420       1430       1440 
LNGGGRSGTF CACATVLEMI RCHSLVDVFF AAKTLRNYKP NMVETMDQYH FCYDVALEYL 
   
EALELR



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    B1AUH1-1-unknown MARAQA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86619
    B1AUH1-19-unknown ETETPA... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    B1AUH1-19-unknown ETETPA... 19 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112185

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ALELR 1446 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ALELR 1446 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt82237

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)