TopFIND 4.0

B2RR83: 3'-5' RNA helicase YTHDC2 {ECO:0000305}

General Information

Protein names
- 3'-5' RNA helicase YTHDC2 {ECO:0000305}
- 3.6.4.13 {ECO:0000269|PubMed:29360036}
- Keen to exit meiosis leaving testes under-populated protein {ECO:0000303|PubMed:29360036}
- Ketu {ECO:0000303|PubMed:29360036}
- YTH domain-containing protein C2 {ECO:0000303|PubMed:28809393}
- mYTHDC2 {ECO:0000303|PubMed:29033321}
Gene names Ythdc2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID B2RR83

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRPSSVSPR PPAPSGGGTG GGGGGSGGGG GGGGGGPASC GPGGGGRAKG LKDIRIDEEV 
        70         80         90        100        110        120 
KIAVNIALER FRYGDQREME FPSSLTSTER AFIHRLSQSL GLVSKSKGKG ANRYLTVKKK 
       130        140        150        160        170        180 
DGSETAHAMM TCNLTHNTKH AVRSLIQRFP VTNKERTELL PKTERGNVFA VEAENREMSK 
       190        200        210        220        230        240 
TSGRLNNGIP QVPVKRGESE FDSFRQSLPV FEKQEEIVKI IKENKVVLIV GETGSGKTTQ 
       250        260        270        280        290        300 
IPQFLLDDCF KNGIPCRIFC TQPRRLAAIA VAERVAAERR ERIGQTIGYQ IRLESRVSPK 
       310        320        330        340        350        360 
TLLTFCTNGV LLRTLMAGDS TLSTVTHVIV DEVHERDRFS DFLLTKLRDL LQKHPTLKLI 
       370        380        390        400        410        420 
LSSAALDVNL FIRYFGSCPV IYIQGRPFEV KEMFLEDILR TTGYTNKEML KYKKEKQREE 
       430        440        450        460        470        480 
KQQTTLTEWY SAQENTFKPE SQRQRAVASV SEEYDLLDDG GDAVFSQLTE KDVNCLEPWL 
       490        500        510        520        530        540 
IKEMDACLSD IWLHKDVDAF AQVFHLILTE NVSVDYRHSE TSATALMVAA GRGFTSQVEQ 
       550        560        570        580        590        600 
LISMGANVHS KASNGWMALD WAKHFGQTEI VDLLESYSAS LEFGNLDESS LVQTNGNDLS 
       610        620        630        640        650        660 
AEDRELLKAY HHSFDDEKVD LDLIMHLLYN ICHSCDAGAI LIFLPGYDEI VGLRDRILFD 
       670        680        690        700        710        720 
DKRFADNTHR YQVFMLHSNM QTSDQKKVLK NPPAGVRKII LSTNIAETSI TVNDVVFVID 
       730        740        750        760        770        780 
SGKVKEKSFD ALNFVTMLKM VWISKASAIQ RKGRAGRCRP GICFRLFSRL RFQNMLEFQT 
       790        800        810        820        830        840 
PELLRMPLQE LCLHTKLLAP VNCTIADFLM KAPEPPPALI VRNAVQMLKT IDAMDAWEDL 
       850        860        870        880        890        900 
TELGYHLADL PVEPHLGKMV LCAVVLKCLD PILTIACTLA YRDPFVLPTQ ASQKRAAMLC 
       910        920        930        940        950        960 
RKRFTAGTFS DHMALLRAFQ AWQKARSDGW ERAFCEKNFL SQATMEIIIG MRTQLLGQLR 
       970        980        990       1000       1010       1020 
ASGFVRARGG GDIRDVNTNS ENWAVVKAAL VAGMYPNLVH VDRENVILTG PKEKKVRFHP 
      1030       1040       1050       1060       1070       1080 
TSVLSQPQYK KIPPANGQAA AIQALPTDWL IYDEMTRAHR IANIRCCSAV TPVTVLVFCG 
      1090       1100       1110       1120       1130       1140 
PARLASNALQ EPSSFRADGI PNDSSDSEME DRTTANLAAL KLDEWLNFKL EPEAASLLLQ 
      1150       1160       1170       1180       1190       1200 
LRQKWHSLFL RRMRAPSKPW SQVDEATIRA IIAVLSTEEQ SAGLQQPSGI GQRPRPMSSE 
      1210       1220       1230       1240       1250       1260 
ELPLASSWRS NNSRKSTADT EFADGSTTGE RVLMKSPSPA LHPPQKYKDR GILHPKRSTD 
      1270       1280       1290       1300       1310       1320 
DRSDQSSVKS TDSSSYPSPC ASPSPPSSGK GSKSPSPRPN MPIRYFIMKS SNLRNLEISQ 
      1330       1340       1350       1360       1370       1380 
QKGIWSTTPS NERKLNRAFW ESSMVYLVFS VQGSGHFQGF SRMSSEIGRE KSQDWGSAGL 
      1390       1400       1410       1420       1430       1440 
GGVFKVEWIR KESLPFQFAH HLLNPWNDNK KVQISRDGQE LEPQVGEQLL QLWERLPLGE 
   
KTTSD

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    B2RR83-1-unknown MSRPSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KTTSD 1445 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)