TopFIND 4.0

B2RUP2: Protein unc-13 homolog D

General Information

Protein names
- Protein unc-13 homolog D
- Munc13-4
Gene names Unc13d
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID B2RUP2

1

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATHLSHPQR RPLLRQAIKI RRRRVRDLQD PPPQATQEVQ VQSHHFSPEE RDLLYEEALY 
        70         80         90        100        110        120 
TVLHRLGQPE PNHVKEASEL LSYLQEAFQV QPEEHQQMLR RVRELEKPVF CLKATVKQAK 
       130        140        150        160        170        180 
GILGKDVSGF SDPYCLLGIE QKVGVAEGSP VSRRRQKAVV KHTIPEEETH RTQVKSQTLN 
       190        200        210        220        230        240 
PVWDETFILE FEDIANASFH LDMWDLDTVE SVRQKLGELT DLHGLRRIFK EARKDKGQDD 
       250        260        270        280        290        300 
FLGNVVLRLQ DLRCREDQWF PLEPCTETYP DRGQCHLQFQ FIHKRRATAA SRSQPSYTVH 
       310        320        330        340        350        360 
FHLLQQLVSH EVTQHQAGST SWDASLSPQA VTILFLHATQ KDLSDFHQSM AQWLAYSRLY 
       370        380        390        400        410        420 
QSLEFPSSCL LHPITSIEYQ WIQGRLKAEQ REELATSFTS LLAYGLSLIR KFRSVFPLSV 
       430        440        450        460        470        480 
SDSPSRLQSL LRVLVQMCKM KAFGELCPDS APLSQLVSEA LRMGTVEWFH LMQQHHQPMV 
       490        500        510        520        530        540 
QGILEAGKAL LNLVQDVMGD LYQCRRTWNK IFHNVLKIDL FSMAFLELQW LVAKRVQDHT 
       550        560        570        580        590        600 
VAAGNLVSPD IGESLFQLYV SLKELCQLGP VPSDSREVLA LDGFHRWFQP AIPSWLQKTY 
       610        620        630        640        650        660 
SVALERVQRA VQMDTLVPLG ELTKHSTSAV DLSTCFAQIS HTARQLDWPD PEEAFMITVK 
       670        680        690        700        710        720 
FVEDTCRLAL VYCSLIKARA RELSAVQKDQ SQAADMLCVV VNNMEQLRLI IDKLPTQLAW 
       730        740        750        760        770        780 
EALEQRVGAV LEEGQLQNTL HAQLQGALAG LGHEIRTGVR TLAEQLEVGI ATHIQKLIGV 
       790        800        810        820        830        840 
KESVLPEDAI LPLMKFLEVK LCYMNTNLVQ ENFSSLLTLL WTHTLTVLVE VASSQRSSSL 
       850        860        870        880        890        900 
ASGRLKVALQ NLEVCFHAEG CGLPPEALHT DTFQALQNDL ELQAASSREL IQKYFCSRIQ 
       910        920        930        940        950        960 
QQAETTSERL GAVTVKVSYR ASEQRLRVEL LSASSLLPLD SNGSSDPFVQ LTLEPRHEFP 
       970        980        990       1000       1010       1020 
EVAPRETQKH KKELHPLFDE TFEFLVPAEP CQKAWACLLL TVLDHDRLGA DDLEGEAFLP 
      1030       1040       1050       1060       1070       1080 
LCRVPGLTDC AEPGEAPQMR LPLTYPAPNG DPILRLLESR KGDREAQAFV KLRRQRAKQA 
   
SQHAP

Isoforms

- Isoform 2 of Protein unc-13 homolog D

Sequence View

        10         20         30         40         50         60 
MATHLSHPQR RPLLRQAIKI RRRRVRDLQD PPPQATQEVQ VQSHHFSPEE RDLLYEEALY 
        70         80         90        100        110        120 
TVLHRLGQPE PNHVKEASEL LSYLQEAFQV QPEEHQQMLR RVRELEKPVF CLKATVKQAK 
       130        140        150        160        170        180 
GILGKDVSGF SDPYCLLGIE QKVGVAEGSP VSRRRQKAVV KHTIPEEETH RTQVKSQTLN 
       190        200        210        220        230        240 
PVWDETFILE FEDIANASFH LDMWDLDTVE SVRQKLGELT DLHGLRRIFK EARKDKGQDD 
       250        260        270        280        290        300 
FLGNVVLRLQ DLRCREDQWF PLEPCTETYP DRGQCHLQFQ FIHKRRATAA SRSQPSYTVH 
       310        320        330        340        350        360 
FHLLQQLVSH EVTQHQAGST SWDASLSPQA VTILFLHATQ KDLSDFHQSM AQWLAYSRLY 
       370        380        390        400        410        420 
QSLEFPSSCL LHPITSIEYQ WIQGRLKAEQ REELATSFTS LLAYGLSLIR KFRSVFPLSV 
       430        440        450        460        470        480 
SDSPSRLQSL LRVLVQMCKM KAFGELCPDS APLSQLVSEA LRMGTVEWFH LMQQHHQPMV 
       490        500        510        520        530        540 
QGILEAGKAL LNLVQDVMGD LYQCRRTWNK IFHNVLKIDL FSMAFLELQW LVAKRVQDHT 
       550        560        570        580        590        600 
VAAGNLVSPD IGESLFQLYV SLKELCQLGP VPSDSREVLA LDGFHRWFQP AIPSWLQKTY 
       610        620        630        640        650        660 
SVALERVQRA VQMDTLVPLG ELTKHSTSAV DLSTCFAQIS HTARQLDWPD PEEAFMITVK 
       670        680        690        700        710        720 
FVEDTCRLAL VYCSLIKARA RELSAVQKDQ SQAADMLCVV VNNMEQLRLI IDKLPTQLAW 
       730        740        750        760        770        780 
EALEQRVGAV LEEGQLQNTL HAQLQGALAG LGHEIRTGVR TLAEQLEVGI ATHIQKLIGV 
       790        800        810        820        830        840 
KESVLPEDAI LPLMKFLEVK LCYMNTNLVQ ENFSSLLTLL WTHTLTVLVE VASSQRSSSL 
       850        860        870        880        890        900 
ASGRLKVALQ NLEVCFHAEG CGLPPEALHT DTFQALQNDL ELQAASSREL IQKYFCSRIQ 
       910        920        930        940        950        960 
QQAETTSERL GAVTVKVSYR ASEQRLRVEL LSASSLLPLD SNGSSDPFVQ LTLEPRHEFP 
       970        980        990       1000       1010       1020 
EVAPRETQKH KKELHPLFDE TFEFLVPAEP CQKAWACLLL TVLDHDRLGA DDLEGEAFLP 
      1030       1040       1050       1060       1070       1080 
LCRVPGLTDC AEPGEAPQMR LPLTYPAPNG DPILRLLESR KGDREAQAFV KLRRQRAKQA 
   
SQHAP



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    B2RUP2-1-unknown MATHLS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    B2RUP2-1-unknown MATHLS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93891

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)