TopFIND 4.0

B2RYM5: Lys-63-specific deubiquitinase BRCC36

General Information

Protein names
- Lys-63-specific deubiquitinase BRCC36
- 3.4.19.- {ECO:0000250|UniProtKB:P46736}
- BRCA1-A complex subunit BRCC36
- BRCA1/BRCA2-containing complex subunit 3
- BRCA1/BRCA2-containing complex subunit 36
- BRISC complex subunit BRCC36
Gene names Brcc3
Organism Rattus norvegicus
Protease Family
Protease ID M67.004
Chromosome location
UniProt ID B2RYM5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAVPVVQAVQ AVHLESDAFL VCLNHALSTE KEEVMGLCIG ELNDDVRSES KFAHAGSDVC 
        70         80         90        100        110        120 
TVPEKVDSIR VVHIHSVIIL RRSDKRKDRV EISPEQLSAA STEAERLAEL TGRPMRVVGW 
       130        140        150        160        170        180 
YHSHPHITVW PSHVDVRTQA MYQMMDQGFV GLIFSCFIED KNTKTGRVLY TCFQSVQAQK 
       190        200        210        220        230        240 
SSDYERIEIP VHVVPHVTIG KVCLESAVEL PKILCQEEQD AYRRIHSLTH LDSVTKIHNG 
       250        260        270        280        290    
SVFTKNLCSQ MSAVSGPLLQ WLEDRLEQNQ QHLRELQREK EELMAELRSL E

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    B2RYM5-2-unknown MAVPVV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    B2RYM5-2-Acetylation AVPVVQ... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LRSLE 291 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)