TopFIND 4.0

D3ZA76: Serine protease HTRA3

General Information

Protein names
- Serine protease HTRA3
- 3.4.21.-
- High-temperature requirement factor A3
- Pregnancy-related serine protease
Gene names Htra3
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID D3ZA76

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQARALLPAT LATLATLAVS VLAREPPAAP CPARCDVSRC PSPRCPGGYV PDLCNCCLVC 
        70         80         90        100        110        120 
AASEGEPCGR PLDSPCGDSL ECVRGVCRCR WTHTVCGTDG HTYADVCALQ AASRRALQIS 
       130        140        150        160        170        180 
GTPVRQLQKG ACPSGLHQLT SPRYKFNFIA DVVEKIAPAV VHIELFLRHP LFGRNVPLSS 
       190        200        210        220        230        240 
GSGFIMSEAG LIVTNAHVVS SSNTASGRQQ LKVQLQNGDA YEATIQDIDK KSDIATILIH 
       250        260        270        280        290        300 
PNKKLPVLLL GHSADLRPGE FVVAIGSPFA LQNTVTTGIV STAQRDGKEL GLRDSDMDYI 
       310        320        330        340        350        360 
QTDAIINYGN SGGPLVNLDG EVIGINTLKV AAGISFAIPS DRITRFLSEF QDKHVKDWKK 
       370        380        390        400        410        420 
RFIGIRMRTI TPSLVEELKT ANPDFPAVSS GIYVQEVVPN SPSQRGGIQD GDIIVKVNGR 
       430        440        450    
PLVDSSELQE AVLNESSLLL EVRRGNDDLL FSIMPEVVM

Isoforms

- Isoform 2 of Serine protease HTRA3

Sequence View

        10         20         30         40         50         60 
MQARALLPAT LATLATLAVS VLAREPPAAP CPARCDVSRC PSPRCPGGYV PDLCNCCLVC 
        70         80         90        100        110        120 
AASEGEPCGR PLDSPCGDSL ECVRGVCRCR WTHTVCGTDG HTYADVCALQ AASRRALQIS 
       130        140        150        160        170        180 
GTPVRQLQKG ACPSGLHQLT SPRYKFNFIA DVVEKIAPAV VHIELFLRHP LFGRNVPLSS 
       190        200        210        220        230        240 
GSGFIMSEAG LIVTNAHVVS SSNTASGRQQ LKVQLQNGDA YEATIQDIDK KSDIATILIH 
       250        260        270        280        290        300 
PNKKLPVLLL GHSADLRPGE FVVAIGSPFA LQNTVTTGIV STAQRDGKEL GLRDSDMDYI 
       310        320        330        340        350        360 
QTDAIINYGN SGGPLVNLDG EVIGINTLKV AAGISFAIPS DRITRFLSEF QDKHVKDWKK 
       370        380        390        400        410        420 
RFIGIRMRTI TPSLVEELKT ANPDFPAVSS GIYVQEVVPN SPSQRGGIQD GDIIVKVNGR 
       430        440        450    
PLVDSSELQE AVLNESSLLL EVRRGNDDLL FSIMPEVVM



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    D3ZA76-1-unknown MQARAL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192778
    D3ZA76-24-unknown REPPAA... 24 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    D3ZA76-24-unknown REPPAA... 24 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt195343

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PEVVM 459 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)