TopFIND 4.0

D3ZDI6: E3 ubiquitin-protein ligase MYLIP

General Information

Protein names
- E3 ubiquitin-protein ligase MYLIP
- 2.3.2.27
- Inducible degrader of the LDL-receptor
- Idol
- Myosin regulatory light chain interacting protein
- MIR
- RING-type E3 ubiquitin transferase MYLIP {ECO:0000305}
Gene names Mylip
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID D3ZDI6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN 
        70         80         90        100        110        120 
RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KESLLAGHLQ CSPEQAVELS 
       130        140        150        160        170        180 
ALLAQTKFGD YNQNTAQYSY EDLCEKELSS STLNSIVGKH KELEGISQAS AEYQVLQIVS 
       190        200        210        220        230        240 
AMENYGIEWH AVRDSEGQKL LIGVGPEGIS ICKEDFSPIN RIAYPVVQMA TQSGKNVYLT 
       250        260        270        280        290        300 
VTKESGNSIV LLFKMISTRA ASGLYRAITE THAFYRCDTV TSAVMMQYSR DLKGHLASLF 
       310        320        330        340        350        360 
LNENINLGKK YVFDIKRTSK EVYDHARRAL YNAGVVDLVS RNDQSPPSSP LKSSDSSMSC 
       370        380        390        400        410        420 
SSCEGLSCQQ TRVLQEKLRK LKEAMLCMVC CEEEINSTFC PCGHTVCCES CAAQLQSCPV 
       430        440    
CRSRVEHVQH VYLPTHTSLL NLTVI

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    D3ZDI6-1-unknown MLCYVT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NLTVI 445 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)