TopFIND 4.0

D3ZTE0: Coagulation factor XII

General Information

Protein names
- Coagulation factor XII
- 3.4.21.38
- Hageman factor
- HAF
- Coagulation factor XIIa heavy chain
- Coagulation factor XIIa light chain
Gene names F12
Organism Rattus norvegicus
Protease Family
Protease ID S01.211
Chromosome location
UniProt ID D3ZTE0

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTALLFLGSL LMSLDLTLSA PPWKSKEFKD GAGDPSVVLT VDGKLCHFPF QYHRRLYHKC 
        70         80         90        100        110        120 
IHKGQPGSRP WCATTPNFDE DQQWGYCLEP KKVKDHCSKH SPCHKGGTCV NTPNGPHCLC 
       130        140        150        160        170        180 
PEHLTGKHCQ REKCFESQLL KFFHENEIWF RTGPGGVARC QCKGPQAVCK LLTSQVCRVN 
       190        200        210        220        230        240 
PCLNGGTCLL VEDHRLCHCP AGYAGPFCDL DLKATCYEDR GLSYRGQAKT TLSGAPCQRW 
       250        260        270        280        290        300 
ASEATYRNMT ETQALSWGLG HHAFCRNPDN DTRPWCYVWS GDRLSWDYCD LEQCQMPTLT 
       310        320        330        340        350        360 
SPVSPESHDM LKPRPPILQS SPRDSTRNQN VVSRTSTVVC GQRFRKRLSS LRRVVGGLVA 
       370        380        390        400        410        420 
LPGSHPYIAA LYWGDSFCAG SLIDPCWVLT AAHCLQKRPA PEELTVVLGQ DRHNQSCERC 
       430        440        450        460        470        480 
QTLAVHSYRL HEGFSSKTYQ HDLALLRLRG RKNSCAILSP HVQPVCLPSS AAPPSETVLC 
       490        500        510        520        530        540 
EVAGWGHQFE GAEEYATFLQ EAQVPFISLD RCSSSNVHGD AILPGMLCAG FLEGGADACQ 
       550        560        570        580        590    
GDSGGPLVCD EGVTERQLTL RGVISWGSGC GDRNKPGVYT DVANYLDWIQ EHTAF

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    D3ZTE0-20-unknown APPWKS... 20 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    D3ZTE0-354-unknown VVGGLV... 354 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SSLRRV 353 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EHTAF 595 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)