TopFIND 4.0

E9Q4S1: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

General Information

Protein names
- High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
- PDE8B
- 3.1.4.53
- Cell proliferation-inducing gene 22 protein
Gene names Pde8b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID E9Q4S1

1

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGCAPSIHVS QSGVIYCRDS DESNSPRQTS SVSQGPTAPL HGLFVQTDAA DAMPPSRAAG 
        70         80         90        100        110        120 
PPGAVRVRRS RAELGSGSST GSSGPATTTC RGRRRHCCSS AEAETQTSYT SVKVLLIFAK 
       130        140        150        160        170        180 
EDSQSDGFWW ACDRAGYRCN IARTPESALE CFLDKHHEII VIDHRQSRNF DAEAVCRSIR 
       190        200        210        220        230        240 
ATNPSEHTVI LAVVSQASDD HEEASVLPLL HAGFNRRFME NSSIIACYNE LIQIEHGEVR 
       250        260        270        280        290        300 
SQFKLRACNS VFTALDHCHE AIEITSDDHV IQYVNPAFER MMGYHKGELL GKELADLPKS 
       310        320        330        340        350        360 
DKNRADLLDT INTCIKKGKE WQGVYYARRK SGDSIQQHVK ITPVIGQGGK IRHFVSLKKL 
       370        380        390        400        410        420 
CCTTDSNKQI HRIHRDSGDN SQTEPHSFRH KSRRKESIDV KSISSRGSDA PSLQNRRYPS 
       430        440        450        460        470        480 
MARIHSMTIE APITKVINII NAAQENSPVT VAEALDRVLE ILRTTELYSP QLGTKDEDPH 
       490        500        510        520        530        540 
TSDLVGGLMT DGLRRLSGNE YVFTKNVHHS HSHLSMPITI NDVPPSIAQL LDNEESWDFN 
       550        560        570        580        590        600 
IFELEAVTHK RPLVYLGLKV FSRFGVCEFL NCTETTLRAW LQVIEANYHS SNAYHNSTHA 
       610        620        630        640        650        660 
ADVLHATAFF LGKERVKGSL DQLDEVAALI AATVHDVDHP GRTNSFLCNA GSELAVLYND 
       670        680        690        700        710        720 
TAVLESHHTA LAFQLTVKDT KCNIFKNIDR NHYRTLRQAI IDMVLATEMT KHFEHVNKFV 
       730        740        750        760        770        780 
NSINKPLAAE SEGSDCECNP TGKNFPENQI LIKRMMIKCA DVANPCRPLD LCIEWAGRIS 
       790        800        810        820        830        840 
EEYFAQTDEE KRQGLPVVMP VFDRNTCSIP KSQISFIDYF ITDMFDAWDA FAHLPALMQH 
       850        860    
LADNYKHWKT LDDLKCKTLR LPSDS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    E9Q4S1-1-unknown MGCAPS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)