TopFIND 4.0

F1LNJ2: U5 small nuclear ribonucleoprotein 200 kDa helicase

General Information

Protein names
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- 3.6.4.13 {ECO:0000250|UniProtKB:O75643}
- BRR2 homolog
- U5 snRNP-specific 200 kDa protein
- U5-200KD
Gene names Snrnp200
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID F1LNJ2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADVTARSLQ YEYKANSNLV LQADRSLIDR TRRDEPTGEV LSLVGKLEGT RMGDKAQRTK 
        70         80         90        100        110        120 
PQMQEERRAK RRKRDEDRHD INKMKGYTLL SEGIDEMVGI IYKPKTKETR ETYEVLLSFI 
       130        140        150        160        170        180 
QAALGDQPRD ILCGAADEVL AVLKNEKLRD KERRREIDLL LGQTDDTRYH VLVNLGKKIT 
       190        200        210        220        230        240 
DYGGDKEIQN MDDNIDETYG VNVQFESDEE EGDEDVYGEV REEASDDDME GDEAVVRCTL 
       250        260        270        280        290        300 
SANLVASGEL MSSKKKDLHP RDIDAFWLQR QLSRFYDDAI VSQKKADEVL EILKTASDDR 
       310        320        330        340        350        360 
ECENQLVLLL GFNTFDFIKV LRQHRMMILY CTLLASAQSE AEKERIMGKM EADPELSKFL 
       370        380        390        400        410        420 
YQLHETEKED LIREERSRRE RVRQSRMDTD LETMDLDQGG EALAPRQVLD LEDLVFTQGS 
       430        440        450        460        470        480 
HFMANKRCQL PDGSFRRQRK GYEEVHVPAL KPKPFGSEEQ LLPVEKLPKY AQAGFEGFKT 
       490        500        510        520        530        540 
LNRIQSKLYR AALETDENLL LCAPTGAGKT NVALMCMLRE IGKHINMDGT INVDDFKIIY 
       550        560        570        580        590        600 
IAPMRSLVQE MVGSFGKRLA TYGITVAELT GDHQLCKEEI SATQIIVCTP EKWDIITRKG 
       610        620        630        640        650        660 
GERTYTQLVR LIVLDEIHLL HDDRGPVLEA LVARAIRNIE MTQEDVRLIG LSATLPNYED 
       670        680        690        700        710        720 
VATFLRVDPA KGLFYFDNSF RPVPLEQTYV GITEKKAIKR FQIMNEIVYE KIMEHAGKNQ 
       730        740        750        760        770        780 
VLVFVHSRKE TGKTARAIRD MCLEKDTLGL FLREGSASTE VLRTEAEQCK NLELKDLLPY 
       790        800        810        820        830        840 
GFAIHHAGMT RVDRTLVEDL FADKHIQVLV STATLAWGVN LPAHTVIIKG TQVYSPEKGR 
       850        860        870        880        890        900 
WTELGALDIL QMLGRAGRPQ YDTKGEGILI TSHGELQYYL SLLNQQLPIE SQMVSKLPDM 
       910        920        930        940        950        960 
LNAEIVLGNV QNAKDAVNWL GYAYLYIRML RSPTLYGISH DDLKGDPLLD QRRLDLVHTA 
       970        980        990       1000       1010       1020 
ALMLDKNNLV KYDKKTGNFQ VTELGRIASH YYITNDTVQT YNQLLKPTLS EIELFRVFSL 
      1030       1040       1050       1060       1070       1080 
SSEFKNITVR EEEKLELQKL LERVPIPVKE SIEEPSAKIN VLLQAFISQL KLEGFALMAD 
      1090       1100       1110       1120       1130       1140 
MVYVTQSAGR LMRAIFEIVL NRGWAQLTDK TLNLCKMIDK RMWQSMCPLR QFRKLPEEVV 
      1150       1160       1170       1180       1190       1200 
KKIEKKNFPF ERLYDLNHNE IGELIRMPKM GKTIHKYVHL FPKLELSVHL QPITRSTLKV 
      1210       1220       1230       1240       1250       1260 
ELTITPDFQW DEKARLVHGS SEAFWILVED VDSEVILHHE YFLLKAKYAQ DEHLITFFVP 
      1270       1280       1290       1300       1310       1320 
VFEPLPPQYF IRVVSDRWLS CETQLPVSFR HLILPEKYPP PTELLDLQPL PVSALRNSAF 
      1330       1340       1350       1360       1370       1380 
ESLYQDKFPF FNPIQTQVFN TVYNSDDNVF VGAPTGSGKT ICAEFAILRM LLQNSEGRCV 
      1390       1400       1410       1420       1430       1440 
YITPMEALAE QVYMDWYEKF QDRLNKKVVL LTGETSTDLK LLGKGNIIIS TPEKWDILSR 
      1450       1460       1470       1480       1490       1500 
RWKQRKNVQN INLFVVDEVH LIGGENGPVL EVICSRMRYI SSQIERPIRI VALSSSLSNA 
      1510       1520       1530       1540       1550       1560 
KDVAHWLGCS ATSTFNFHPN VRPVPLELHI QGFNISHTQT RLLSMAKPVY HAITKHSPKK 
      1570       1580       1590       1600       1610       1620 
PVIVFVPSRK QTRLTAIDIL TTCAADIQRQ RFLHCTEKDL IPYLEKLSDS TLKETLLNGV 
      1630       1640       1650       1660       1670       1680 
GYLHEGLSPM ERRLVEQLFS SGAIQVVVAS RSLCWGMNVA AHLVIIMDTQ YYNGKIHAYV 
      1690       1700       1710       1720       1730       1740 
DYPIYDVLQM VGHANRPLQD DEGRCVIMCQ GSKKDFFKKF LYEPLPVESH LDHCMHDHFN 
      1750       1760       1770       1780       1790       1800 
AEIVTKTIEN KQDAVDYLTW TFLYRRMTQN PNYYNLQGIS HRHLSDHLSE LVEQTLSDLE 
      1810       1820       1830       1840       1850       1860 
QSKCISIEDE MDVAPLNLGM IAAYYYINYT TIELFSMSLN AKTKVRGLIE IISNAAEYEN 
      1870       1880       1890       1900       1910       1920 
IPIRHHEDNL LRQLAQKVPH KLNNPKFNDP HVKTNLLLQA HLSRMQLSAE LQSDTEEILS 
      1930       1940       1950       1960       1970       1980 
KAIRLIQACV DVLSSNGWLS PALAAMELAQ MVTQAMWSKD SYLKQLPHFT SEHIKRCTDK 
      1990       2000       2010       2020       2030       2040 
GVESVFDIME MEDEERNALL QLTDSQIADV ARFCNRYPNI ELSYEVVDKD SIRSGGPVVV 
      2050       2060       2070       2080       2090       2100 
LVQLEREEEV TGPVIAPLFP QKREEGWWVV IGDAKSNSLI SIKRLTLQQK AKVKLDFVAP 
      2110       2120       2130    
ATGGHNYTLY FMSDAYMGCD QEYKFSVDVK EAETDSDSD

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    F1LNJ2-1-unknown MADVTA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DSDSD 2139 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)